Preparation method of effective ingredient of isatis root

An active ingredient, isatis root technology, applied in the directions of medical preparations containing active ingredients, plant/algae/fungus/moss ingredients, pharmaceutical formulations, etc., can solve the problems of high cost, inconvenience in refining, high product cost, and achieve good social benefits and economic benefits, reducing human error, and improving product yield

Inactive Publication Date: 2011-09-28
SICHUAN TAIXIN ANIMAL PHARMA
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AI Technical Summary

Problems solved by technology

But there are also many shortcomings, such as the problems of high decoction temperature, long time, and large energy consumption; in terms of retaining active ingredients and removing ineffective ingredients, there are large loss of active ingredients, long cycle, many processes, and low extraction rate. The problem is not high; at the same time, the extract contains more impurities, which brings inconvenience to the next step of refining, thus affecting the extraction rate of active ingredients; the commonly used water extraction and alcohol precipitation method to remove impurities and refine, due to the use of a large amount of organic solvents, the safety is poor, Recycling is cumbersome, costly, and seriously pollutes the environment
The original process of preparing the active ingredients of Radix isatidis is produced by decoction and ethanol precipitation, which has many disadvantages such as high decoction temperature, long time, large energy consumption, large loss of active ingredients, many processes, low extraction rate, and environmental pollution. The product qualification rate is extremely low, resulting in high product costs and affecting the economic benefits of the enterprise

Method used

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  • Preparation method of effective ingredient of isatis root
  • Preparation method of effective ingredient of isatis root

Examples

Experimental program
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Effect test

Embodiment 1

[0024] according to figure 1 Shown, a kind of preparation method of Radix Radix Radix active ingredient comprises the following steps:

[0025] (1) Screening: pick out the moth-eaten and moldy products and impurities of Radix Radix, sieve out the sediment, select medicinal parts and remove non-medicinal parts;

[0026] (2) Cleaning: Put the Radix Radix Radix medicinal material after screening into clear water, and take it out in time after washing;

[0027] (3) drying: the washed Radix isatidis medicinal material is dried in time, the temperature is controlled at 70°C, and the water content reaches below 8%;

[0028] (4) Pulverizing: the Radix Radix Radix medicinal material of drying is pulverized into coarse powder, crosses 20 mesh sieves;

[0029] (5) One-level extraction: 100Kg of Radix Radix isatidis coarse powder after pulverizing, carry out continuous counter-current extraction with chloroform extraction solution 520L by the three-stage decanter connected in series;

...

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Abstract

The invention discloses a method for preparing active ingredients of radix isatidis, including steps of filtering, cleaning, drying, pulverizing, stage-one extracting, stage-one centrifugating, stage-two extracting, stage-one fractionating, stage-two centrifugating, stage-three extracting, stage-two fractionating and precipitating radix isatidis, thereby obtaining a finished active ingredients ofradix isatidis. The method has the advantages of high yield, high output, energy saving, short production period and full automatic control. The prepared product has the functions of antibiosis, antivirus, antiendotoxin, anti-inflammation and immunity strengthening, and can be made into liquid injection, tablet, pill, powder, capsule, oral solution, etc.

Description

technical field [0001] The invention relates to a preparation method of a Chinese herbal medicine extract, in particular to a preparation method of an active ingredient of Radix isatidis, belonging to the field of traditional Chinese medicines. Background technique [0002] Isatis root is the root of the cruciferous plant Isatis indigo, which has the effects of clearing away heat, detoxifying and cooling blood. Radix Radix Radix Radix Extract contains polyglucoside, indirubin, indirubin, indigo, lumbroside, BETA-sitosterol, adenosine, palmitic acid and various amino acids, which have antibacterial, antiviral, antiendotoxin, Anti-inflammatory, enhance immune function and other characteristics. However, Banlanban, like other Chinese herbal medicines, has very complex ingredients, including active ingredients, invalid ingredients and toxic ingredients. In order to improve the therapeutic effect of Radix Radix and other Chinese herbal medicines, it is necessary to extract the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/19A61K36/315A61P31/04A61P31/12A61P29/00A61P37/04A61K125/00
Inventor 冯建国
Owner SICHUAN TAIXIN ANIMAL PHARMA
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