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Stomach cancer diagnostic method

A diagnostic method and technology for gastric cancer, applied in the field of medical diagnosis, can solve problems such as misdiagnosis and loss of treatment opportunities for patients, and achieve the effects of less time-consuming, good clinical application value, good sensitivity and specificity

Inactive Publication Date: 2009-03-11
RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

Consequently, the frequency of false-negative tests is very high, leading to missed opportunities for treatment, and the use of these markers may give false-positive signals in up to 1 / 3 of individuals with benign gastric disease, leading to misdiagnosis

Method used

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  • Stomach cancer diagnostic method
  • Stomach cancer diagnostic method
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Examples

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Embodiment Construction

[0038] Below in conjunction with specific embodiment, further illustrate the present invention. It should be understood that these examples are only used to illustrate the present invention and are not intended to limit the scope of the present invention. For the experimental methods without specific conditions indicated in the following examples, the conventional conditions or the conditions suggested by the manufacturer are usually followed. Ratios and percentages are by weight unless otherwise indicated.

[0039] Reagents and instruments: L-2-chlorophenylalanine, ethyl chloroformate, pyridine, absolute ethanol, sodium hydroxide, chloroform, anhydrous sodium sulfate (the above reagents are of analytical grade, produced by Shanghai Chemical Reagent Company) . KQ-250DB CNC ultrasonic cleaner (produced by Kunshan Ultrasonic Instrument Co., Ltd.). LD5-2A desktop centrifuge (Beijing Jingli Centrifuge Co., Ltd.). Gas chromatography mass spectrometer TurboMass (produced by Perk...

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Abstract

The invention relates to the technical field of medical diagnosis, in particular to a stomach cancer diagnostic method which comprises the steps: a urine sample of a tested person is collected; the content of target molecules in the urine sample is detected, the target molecule is one or two or three or four or five or six of isoleucine, threonine, proline, methionine, tyrosine or glycin; the numerical value of the content of the target molecules is analyzed; when the content of the target molecules of the tested person is higher than the diagnosis experiment critical point, the tested person is considered as the stomach cancer patient. The stomach cancer diagnostic method has good sensitivity and specificity, simple structure, and less time consuming, simultaneously, adopts the urine as the tested sample so as to avoid bringing body pain to the patients by adopting tissues and blood, thus having good clinical application value viewing from the patient compliance and the correct rate of the detection result.

Description

technical field [0001] The invention relates to the technical field of medical diagnosis, in particular to a method for diagnosing gastric cancer. Background technique [0002] Gastric cancer is one of the most common and deadly malignant tumors in the world, and it is also one of the most common malignant tumors in my country. The rate has remained high. Statistics show that there are 400,000 new gastric cancer patients and 300,000 deaths every year in my country, and the proportion of young people suffering from gastric cancer is increasing, and 15% of the patients are young people under the age of 40. Early diagnosis of gastric cancer is difficult, and the 5-year survival rate is less than 20% in most western countries. More than 90% of gastric cancers are adenocarcinomas, which can be divided into intestinal type and diffuse type by Lauren classification. [0003] At present, most hospitals mainly rely on X-ray, B-mode ultrasound, endoscopy and biopsy pathological exam...

Claims

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Application Information

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IPC IPC(8): G01N33/48G01N30/00G01N27/64
Inventor 于颖彦陈闽军李作峰徐露王清文静然燕敏朱正纲
Owner RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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