Relieve asthma oral liquid preparation and preparing method thereof
An oral preparation and asthma technology, applied in the field of medicine, can solve the problems of inaccurate dosage, large dosage of traditional Chinese medicine decoction, and inability to commercialize it.
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Embodiment 1
[0047] Embodiment one: Dingchuan decoction extract (extract and volatile oil) preparation method
[0048] Prescription: ginkgo 9g, ephedra 9g, perilla 6g, coltsfoot flower 9g, almond 9g, mulberry bark 9g, scutellaria baicalensis 4.5g, pinellia 9g, licorice 3g
[0049] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 10-15 times the amount of water to soak for 2-10 hours, heat and boil for 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, filtered to get the supernatant, concentrated under reduced pressure to obtain a medicinal extract of about 20.5 g of water extract and about 0.2 g of volatile oil.
Embodiment 2
[0050] Embodiment 2: Dingchuan Decoction oral solid preparation preparation method
[0051] (1) Preparation of Dingchuan Decoction Granules
[0052] prescription:
[0053] Dingchuan Decoction Extract 10-90%
[0054] Starch 5.0-70%
[0055] Dextrin 2.0-20%
[0056] Xylitol 5.0-20%
[0057] Methyl sorbate 0.001-2.0%
[0058] Preferred Prescription:
[0059] Dingchuan Decoction Extract 20.7g
[0060] Starch 8.0g
[0061] Dextrin 8.0g
[0062] Xylitol 4.0g
[0063] Methyl sorbate 0.002g
[0064] Preparation method: Prepare Chai Ding Chuan Decoction extract according to the method in Example 1, add the prescribed amount of auxiliary materials to make granules according to the conventional method, dissolve the volatile oil with an appropriate amount of ethanol, spray evenly on the granules, dry at low temperature, and pack. 10g per bag.
[0065] (2) Preparation of Dingchuan Decoction Effervescent Tablets
[0066] Prescription: Dingchuan Decoction Extract 20.7
[0067...
Embodiment 3
[0103] Embodiment three: Dingchuan decoction oral liquid preparation preparation method
[0104] (1) Preparation of oral liquid
[0105] Prescription: Dingchuan Decoction Extract 5-80%
[0106] Sucrose 5.0-50%
[0107] Sodium cyclamate 5.0-40%
[0108] Methyl sorbate 0.001-2%
[0109] Span 20 5.0-40%
[0110] Distilled water 10-90%.
[0111] Preferred Prescription:
[0112] Dingchuan Decoction Extract 20.7g
[0113] Sucrose 5.0g
[0114] Sodium cyclamate 1.5g
[0115] Span 20 2.5g
[0116] Methyl sorbate 0.02g
[0117] Make up to 60ml with distilled water.
[0118] Preparation method: prepare the extract of Dingchuan decoction according to the method in Example 1, add the excipients of the prescription and distilled water, then ultrafilter through an ultrafilter, fill the ultrafiltrate, and sterilize to obtain the product.
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