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New use of Chinese medicine compound pharmaceutical composition

A composition and drug technology, applied in the field of traditional Chinese medicine compound pharmaceutical compositions, can solve the problems of inconvenience in clinical use, accurate medication, inconvenience for patients, etc., and achieve the effect of no effect on serum estrogen levels, delaying vaginal atrophy, and clear drug efficacy. Effect

Active Publication Date: 2011-06-08
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine has traditional advantages in the treatment of senile diseases. However, for a disease that is accurately diagnosed by Western medicine standards, if there is no formally trained doctor, when clinically applying traditional Chinese medicine, it is often wrong to use it due to inaccurate syndrome differentiation, resulting in clinical symptoms. It is inconvenient to use, it is not convenient for accurate medication of the disease with exact diagnosis, and it also brings inconvenience and waste to patients
At present, there are no related reports about Zuogui Pills and Yougui Pills being used to delay vaginal atrophy

Method used

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  • New use of Chinese medicine compound pharmaceutical composition
  • New use of Chinese medicine compound pharmaceutical composition
  • New use of Chinese medicine compound pharmaceutical composition

Examples

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Effect test

Embodiment 1

[0030] The preparation of embodiment 1 pharmaceutical composition 1 of the present invention (Zuogui pill)

[0031] Weigh raw materials: Rehmannia glutinosa 200g, dodder 100g, achyranthes bidentata 75g, tortoise shell glue 100g, deer horn glue 100g, yam 100g, dogwood 100g, medlar 100g;

[0032] Preparation method: The above eight flavors, except for antler glue and tortoise shell glue, the other six flavors such as rehmannia glutinosa are crushed into fine powder, sieved and mixed. Take deer horn glue and tortoise shell glue to melt, and mix with the above fine powder. For every 100g of powder, add 10g of refined honey and appropriate amount of water, make pills, and dry to obtain.

Embodiment 2

[0033] The preparation of embodiment 2 pharmaceutical composition 2 of the present invention (Yougui pill)

[0034] Weigh raw materials: Rehmannia glutinosa 24g, yam 12g, dogwood 9g, medlar 9g, dodder 12g, antler gum 12g, Eucommia 12g, cinnamon 6g, angelica 9g, aconite 6g.

[0035] Preparation method: Steam the rehmannia glutinosa into a pestle paste, and make the rest into fine powder, add refined honey to make pills, which are as big as marbles. Take two or three pills (6 ~ 9g) every time you chew, and send it down with boiled soup.

Embodiment 3

[0036] Embodiment 3 preparation of medicine of the present invention

[0037] Weigh raw materials: Rehmannia glutinosa 24g, dogwood 12g, yam 12g, medlar 12g, dodder 12g, antler glue 12g;

[0038] Preparation method: The above six flavors, except the antler gum, the other six flavors such as Rehmannia glutinosa are crushed into fine powder, sieved and mixed. Take the antler glue and melt it, and mix it with the above fine powder. Add 10g of refined honey and appropriate amount of water for every 100g of powder.

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Abstract

The present invention provides a medicine compound including the following raw materials with the weight portions such as 18 to 30 portions of prepared rehmannia rhizome, 9 to 12 portions of cornus dogwood fruit, 8 to 16 portions of Chinese yam, 9 to 12 portions of medlar, 8 to 16 portions of field dodder and 8 to 16 portions of deerhorn glue, and the purpose in preparing the medicine for delaying vaginal aging. The medicine is an active medicine for strengthening external gonad tissue aromatase and a medicine for increasing vaginal blood supply. The medicine is a medicine for preventing or / and curing senile vaginitis. Under a specific diagnosis standard, the medicine provided by the present invention has definite efficacy. The medicine has the advantages of same efficacy on delaying vaginal aging, few raw materials, wide sources, effective cost saving due to selection of raw materials, no effect on the level of serum estrogen after long-term administration, no proliferation on endometrium and safety. The present invention provides a new choice for clinically curing senile vaginitis, in particular preventing senile vaginitis or recurrence of senile vaginitis.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine compound pharmaceutical composition, in particular, an application in preparing a medicine for delaying vaginal atrophy. Background technique [0002] Estrogen mainly exists in two molecular forms: estrone (Estrone, E 1 ) and estradiol (Estradiol, E 2 ), E 1 and E 2 can be transformed into each other. due to E 1 The biological activity is only E 2 1% or so, so E 2 It is a physiologically significant estrogen molecule. The ovary of premenopausal non-pregnant women is the main organ for the synthesis of estrogen, which converts testosterone (Te) into E 2 ;Other sites can also synthesize a small amount of estrogen, including adipose tissue mesenchymal cells [1] , skin fibroblasts, osteoblasts, osteochondrocytes, cardiovascular endothelial cells and arterial smooth muscle cells. In addition, the preoptic area of ​​the hypothalamus, the anterior part of the hypothalamus, t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61P15/02A61K35/32
Inventor 陆华胡翔黄晓玲
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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