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Chitin water soluble aerosol and wound applied block composite medicine

A technology of chitin and water-soluble gas, which is applied in the field of surgical drugs containing chitin, can solve the problems that can not be cured after one use, and achieve the effect of shortening the treatment time, good performance of absorbing exudate, and long effective period

Inactive Publication Date: 2008-03-26
郭威岩 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current covering materials used for trauma cannot heal after one use, and new covering materials need to be replaced in the middle

Method used

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  • Chitin water soluble aerosol and wound applied block composite medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] Use a 250ml glass jar as a unit of measurement.

[0063] 1. Medical sterile purified water 220ml

[0064] 2. Nanoscale chitin

[0065] Relative molecular weight 3000-1500

[0066] Contains 85-90% decaproyl

[0067] Dosage 1g

[0068] 3. Polyvinyl alcohol "pvA04-88"

[0069] degree of polymerization 40

[0070] Alcoholysis degree 88%

[0071] Dosage 2g

[0072] 4. Glycerin 0.1g

[0073] 5. Acetic acid washout 0.3g

[0074] 6. The dosage of sterile pure liquid chlorine for the propellant is calculated according to the system pressure of 172.4kpa. The maximum burst pressure of the nitrogen aerosol can is not less than 1.4Mp. The 250ml aerosol can is for clinical use in hospitals.

Embodiment 2

[0076] Use a 250ml glass jar as a unit of measurement.

[0077] 1. Medical sterile purified water 220ml

[0078] 2. Nanoscale chitin

[0079] Relative molecular weight 3000-1500

[0080] Contains 85-90% decaproyl

[0081] Dosage 1.5g

[0082] 3. Polyvinyl alcohol "pvA04-88"

[0083] degree of polymerization 40

[0084] Alcoholysis degree 88%

[0085] Dosage 3g

[0086] 4. Glycerin 0.1g

[0087] 5. Acetic acid washout 0.3g

[0088] 6. The dosage of sterile pure liquid chlorine for the propellant is calculated according to the system pressure of 172.4kpa. The maximum burst pressure of the nitrogen aerosol can is not less than 1.4Mp. The 250ml aerosol can is for clinical use in hospitals.

[0089] Nanoscale oligosaccharides in aerosol are biologically active chitin wound healing agents. Polyvinyl alcohol is a hydrophilic thickening, film-forming, slow-release agent. Glycerin is the softening and toughening agent of the polyvinyl alcohol film, which makes the polyvinyl ...

Embodiment 3

[0091] Figure 1 shows the schematic diagram of the composition of the chitin wound dressing, in which 1 is the base cloth layer; 2 is the pressure-sensitive adhesive evenly coated on the base cloth; 3 is the "polyvinyl alcohol" skeleton layer; 4 is the chitin fiber water Barbed gauze application layer.

[0092] The first base fabric layer adopts cotton wool non-woven fabric, and the pressure-sensitive adhesive (PAS) is evenly coated on it, and the second skeleton layer is polyvinyl alcohol, 200 mesh, and contains 20% water.

[0093] The skeleton layer plays the functions of skeleton, sustained release, water absorption, thickening and bonding.

[0094] The third layer is chitin fiber spunlace cloth, that is, mesh non-accumulating fabric, chitin fiber specification is 1.5d (d-denier is the measurement unit of cellulose thickness), cut length 30mm, width 1000mm, with The amount of material is 20-50 g / m 2 . This layer is in direct contact with the wound when used. The product...

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Abstract

The present invention relates to a wates-soluble aerosol made up by using chitosan as main raw material and a chitosan wound mounting block made up by using basic layer, skeleton layer and mounting layer through a certain hot-pressing and integrally-forming process. The nano-grade oligosaccharide in the aerosol is a chitosan wound healing agent with bio-activity, the polyvinyl alcohol is the hydrophilic thickening, film-forming and slow release agent and the glycerine is the flexibilizing and toughening agent of polyvinyl alcohol medicine film.

Description

technical field [0001] The invention relates to the field of drugs for medical wound surgery, in particular to surgical drugs containing chitin. Background technique [0002] Trauma happens to the masses all the time. Natural disasters, traffic accidents, accidents in factories and mines, wars, and negligence in daily life can cause accidental injuries to human bodies. Mild cases are disinfected and bandaged, and rely on their own skin regeneration to heal and recover; severe cases need to be cleaned, disinfected, and changed dressings for a long time to recover; as for more serious injuries, wound skin loss is large, and burns are treated with their own skin. Transplantation (causing skin picking again). In addition to drug treatment, sterilization and anti-inflammation, and immunity enhancement, the wound should also be covered with special medical wound protection materials that have achieved high-tech achievements in the same period. Its products include: special synthe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/722A61K9/12A61K47/32A61P17/02A61F13/02A61L15/44
Inventor 郭威岩郭成孙万清
Owner 郭威岩
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