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Antibacterial dressings manufacturing method for medical purpose and uses thereof

A manufacturing method and technology of non-woven fabrics, applied in dressings, viscous dressings, medical science, etc., can solve the problems of not being able to maintain the fiber state, lowering the yield of carboxymethylated chitosan fibers, and not being able to process medical textiles, etc. Achieve the effect of promoting tissue healing and isolating bacterial infection

Inactive Publication Date: 2010-05-12
LANTOR UK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the limitation of production process, this method cannot carry out carboxymethylation to chitosan fiber or non-woven fabric made of chitosan fiber
It is known to those skilled in the art that if this process is directly applied to the non-woven fabric that chitosan fiber or chitosan fiber are made, because the specific surface area of ​​chitosan fiber is far greater than the specific surface area of ​​chitosan raw material, And chitosan itself has good adsorption, so if operate according to above-mentioned patent method, chitosan fiber will not be able to keep original fiber state, thereby has caused the finished product rate of carboxymethylated chitosan fiber to reduce greatly; And if operate according to above-mentioned patent method, the chitosan fiber of gained will dissolve after absorbing exudate, can't make the medical dressing that has very good wet strength to promote wound healing after absorbing liquid
Its product carboxymethyl chitosan can only be used as a moisturizer and cannot be processed into various medical textiles

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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  • Antibacterial dressings manufacturing method for medical purpose and uses thereof
  • Antibacterial dressings manufacturing method for medical purpose and uses thereof
  • Antibacterial dressings manufacturing method for medical purpose and uses thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] 100 grams of chitosan fibers are immersed in the concentration of 40% NaOH solution, bath ratio 1: 20, and reacted at room temperature for 0.5 hour to generate alkalized chitosan fibers; the product after alkalization is washed with absolute alcohol; The product is then reacted with chloroacetic acid in isopropanol, the concentration of chloroacetic acid is 20%, the reaction temperature is 35°C, and the reaction time is 1 hour. After the reaction is completed, the excess solution is removed, washed with absolute ethanol, and air-dried to form a carboxymethyl shell. polysaccharide fibers. This product is made into 50 g / m by cutting, opening, netting and needle punching 2 The non-woven fabric can be made into a dressing after cutting, packaging and disinfection, which is called a1. Suitable for wounds less than 10cm 2 the wound.

Embodiment 2

[0044] According to the mass ratio of 9:1, the chitosan fiber and the carboxymethyl chitosan fiber used in the preparation of a1 are mixed, opened, netted, and needle-punched to make 100 g / m 2 Non-woven fabric, which can be made into a dressing after cutting, packaging, and disinfection, is called a2. It is suitable for burns and scalds with relatively large trauma.

Embodiment 3

[0046] 100 grams of chitosan fibers are immersed in a concentration of 45% NaOH solution, the bath ratio is 1: 40, and reacted for 1 hour at room temperature to generate alkalized chitosan fibers; the alkalized product is washed with absolute alcohol; The product is then reacted with chloroacetic acid in isopropanol, the concentration of chloroacetic acid is 30%, the reaction temperature is 60°C, and the reaction time is 3 hours. After the reaction is completed, the excess solution is removed, washed with absolute ethanol, and air-dried to form a carboxymethyl shell. polysaccharide fibers. This product is made into 50 g / m by cutting, opening, netting and needle punching 2 Non-woven fabrics can be made into dressings after cutting, packaging and disinfection, called b1. Suitable for wounds less than 10cm 2 the wound.

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Abstract

The present invention discloses a method for making the antibiotic medical dressing, which includes adopting chitosan fiber to generate alkali chitosan fiber by alkalization then doing etherificationreaction with the chloroactic acid, the carboxymethyl chitosan fiber is prepared, and the dressing is prepared after opening packing, fleece formation and needling. Or the chitosan fiber is made intochitosan nonwoven cloth by the processing of the nonwoven cloth, then the dressing is done with carboxymethylation reaction, and the carboxymethyl chitosan antibiotic medical dressing is obtained after cutting, packing and sterilizing. The invention also discloses the usage of the antibiotic medical dressing prepared with the method. The invention is suitable for the surgery wound, burn, scald andother chronic wounds, covering the would surface to prevent the moisture loss in the body fluid, providing an active humid surrounding for the would healing, keeping no dropsy and no erosion at the would surface, isolating the bacterial infection, and obtaining the effects of anti-inflammation, hemostasis, ease pain and facilitating the tissue assimilation.

Description

technical field [0001] The present invention relates to the manufacturing method of medical dressing, especially relates to the manufacturing method of antibacterial medical dressing; In addition, the present invention also relates to the application of this antibacterial medical dressing. Background technique [0002] For a long time, surgical dressings are mainly sterilized cotton and cotton gauze, which have certain limitations in their application. Cotton gauze itself does not have the ability to resist the reproduction of microorganisms. Although it has been sterilized, it is easy to be infected with bacteria during use. These traditional dressings will adhere to the wound during use, and even grow in the new granulation. Cause the patient's pain and the generation of new wound surface in changing dressing process. These traditional dressings also leave some debris after use, which affects wound healing. Dressings made of other synthetic materials suffer from the sam...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/28A61F13/02
Inventor 李毅彬吴清基成立萍
Owner LANTOR UK
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