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Oral composition containing difructose anhydride

A double fructose anhydride and composition technology, applied in the field of oral compositions, can solve the problems of unknown equol, increase calcium absorption, etc., and achieve the goal of enhancing equol production capacity and increasing equol concentration Effect

Inactive Publication Date: 2007-10-17
FUAN KERU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] On the other hand, it is known that difructose anhydride (hereinafter referred to as DFA) has a bifidobacteria proliferation effect (Patent Document 1: Japanese Patent Publication No. 3-5788), increases calcium absorption (Patent Document 2: Japanese Patent Laid-Open No. 11- No. 43438 bulletin), has a diuretic effect (patent document 3: Japanese Patent Laid-Open No. 2003-321371 bulletin), but its effect of enhancing equol production is not yet known

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The enhanced effect of DFA on equol production in the gut was analyzed.

[0025] Get 27 Wistar-ST male rats (6 weeks old), prepare and raise them with solid feed for 3 days, then divide them into 3 groups according to the weight stratification method, each group n=9, give 0.25% isotropic acid containing Basal feed of 40% flavonoid food (Basal diet group), feed in which sucrose in basic feed was replaced with 3% DFAIII as a whole (DFAIII group), feed in which sucrose in basic feed was replaced with 3% fructooligosaccharide as a whole (FOS group), fed for 20 days. On the 20th day, blood was collected from the tail vein, and the concentration of equol (Equol) in plasma was measured by HPLC-UV method.

[0026] The results are shown in Table 1. A and b in the table indicate that there are significant differences between values ​​with different symbols.

[0027] This result shows that DFA raises the concentration of equol (Equol) in blood plasma by taking DFA.

[0028] ...

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PUM

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Abstract

The present invention provides an oral composition for potentiating the production of equol by an intestinal bacterium which contains, as the active ingredient, difructose anhydride for activating the equol productivity of the intestinal bacterium.

Description

technical field [0001] The present invention relates to oral compositions for enhancing equol production by intestinal bacteria. Background technique [0002] The antioxidant activity and estrogenic activity of equol are higher than those of daidzein and genistein, which are representative isoflavones, and its further health effects are expected. Equol is a metabolite of daidzein metabolized by intestinal bacteria in the intestine. By activating the equol production ability of intestinal bacteria, it can be expected that the available equol in the body will increase. [0003] On the other hand, it is known that difructose anhydride (hereinafter referred to as DFA) has a bifidobacteria proliferation effect (Patent Document 1: Japanese Patent Publication No. 3-5788), increases calcium absorption (Patent Document 2: Japanese Patent Laid-Open No. 11- 43438 bulletin), has a diuretic effect (patent document 3: Japanese Patent Laid-Open No. 2003-321371 bulletin), but its effect of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7016A61K31/352A61P1/14A23L1/30A23K1/16C07D311/36C07H3/10A61K31/353A61P43/00C07H3/04
CPCA23L1/30A23K1/1643A23L1/09A61K31/352A61K31/7016A23K20/163A23L29/30A23L33/10A23L5/00A23L33/125A61P1/12A61P1/14A61P43/00Y02A50/30
Inventor 田村亚纪子重松典宏原博
Owner FUAN KERU
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