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Composition for corpse specimen conservation and its preparing process

A technology for compositions and specimens, which is applied in the fields of preserved compositions, corpse antiseptic, and mildew prevention, can solve the problems of environmental pollution, inconvenient operation, high viscosity, etc., and achieve the effects of simple preparation method, easy popularization and application, and good use effect

Inactive Publication Date: 2007-08-08
WENZHOU MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But practice has proved that its most obvious disadvantages are: formaldehyde has a strong pungent smell, pollutes the environment, and seriously endangers the health of anatomy teaching staff and students.
Both of these two corpse preservation solutions use ethanol as an effective antiseptic component, long-term use will cause the specimen protein to harden and deform, and because ethanol is volatile, it is difficult to control the effective concentration during use
Chinese patent CN1233391A discloses a specimen preservation solution that does not contain ethanol and formaldehyde but contains a sodium salt or potassium salt, at least one polyhydroxy color retention agent and water, but contains many polyhydroxy color retention agents. High viscosity, inconvenient operation and high cost, difficult to popularize
At present, it is reported that cyclohexamethylenetetramine (hexamethylenetetramine) and 50% glutaraldehyde are used instead of formaldehyde to preserve cadaver specimens, but the cost of this cadaver preservation solution is high and it is difficult to popularize and apply

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A composition for preservation of corpse specimens, which consists of 4,5-dichloro-2-propylisothiazol-3-one, dodecyltrimethylammonium chloride, potassium nitrate, sodium sulfate, ethylene dichloride Alcohol composition.

[0020] Apply this composition, prepare 1000 liters of cadaver specimen preservation solutions, weigh each component by following weight:

[0021] 4,5-dichloro-2-propylisothiazol-3-one: 1.0kg;

[0022] Dodecyltrimethylammonium chloride: 1.5kg;

[0023] Potassium nitrate: 10.0kg;

[0024] Sodium sulfate: 5.0kg;

[0025] Ethylene glycol: 15.0kg;

[0026] Add tap water to 1000 liters.

[0027] The preparation process of the cadaver specimen preservation solution is as follows:

[0028] First add ethylene glycol and dodecyltrimethylammonium chloride to the 4,5-dichloro-2-propylisothiazol-3-one of the above weight, stir evenly at normal temperature and pressure, then add potassium nitrate, Sodium sulfate is added to 1000 liters with tap water, stirred...

Embodiment 2

[0032] A composition for preservation of corpse specimens, which consists of 4-bromo-5-chloro-2-isoamylisothiazol-3-one, cetyltrimethylammonium chloride, sodium nitrate, magnesium sulfate, Composed of propylene glycol and ethylene glycol.

[0033] Apply this composition, prepare 1000 liters of cadaver specimen preservation solutions, weigh each component by following weight:

[0034] 4-bromo-5-chloro-2-isoamylisothiazol-3-one: 0.8kg;

[0035] Cetyltrimethylammonium chloride: 0.75kg;

[0036] Dimethyl didecyl ammonium chloride: 1.25kg;

[0037] Sodium nitrate: 10.0kg;

[0038] Magnesium sulfate: 5.0kg;

[0039] Propylene glycol: 5.0kg;

[0040] Ethylene glycol: 10.0kg;

[0041] Add tap water to 1000 liters.

[0042] The preparation process of the cadaver specimen preservation solution is as follows:

[0043] First add 4-bromo-5-chloro-2-isoamylisothiazol-3-one with the above weight, add propylene glycol, ethylene glycol, cetyl trimethyl ammonium chloride, dimethyl didec...

Embodiment 3

[0045] A composition for preservation of corpse specimens, which consists of 4-bromo-5-chloro-2-benzylisothiazolin-3-one, 2-(4-thiazolyl) benzimidazole, octyldecyl di Methyl ammonium chloride, zinc nitrate, calcium chloride, propylene glycol, glycerin.

[0046] Apply this composition, prepare 1000 liters of cadaver specimen preservation solutions, weigh each component by following weight:

[0047] 4-Bromo-5-chloro-2-benzylisothiazolin-3-one: 1.0kg;

[0048] 2-(4-thiazolyl)benzimidazole: 0.5kg;

[0049] Octyldecyldimethylammonium chloride: 1.5kg;

[0050] Zinc nitrate: 3.0kg;

[0051] Calcium chloride: 12.0kg;

[0052] Propylene glycol: 7.0kg;

[0053] Glycerol: 8.0kg;

[0054] Add tap water to 1000 liters.

[0055] The preparation process of the cadaver specimen preservation solution is as follows:

[0056] First, add propylene glycol, glycerol, octyldecyldimethyl ammonium chloride, stir evenly at normal temperature and pressure, then add zinc nitrate and calcium chlo...

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PUM

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Abstract

The invention relates to a composite used to store the corpse specimen, which comprises fungus-proof active component, penetration adjuster and humectant, wherein, the fungus-proof active component is heterocyclic compound and quaternary ammonium salt; the penetration adjuster is one, two or the mixture of nitrate, sulfate, or hydrochlorate; the humectant is polyatomic alcohol. The invention also provides relative production. The invention can be used to store the corpse specimen, while the component has long fungus-proof time and high effect, without methyl aldehyde, with low cost.

Description

technical field [0001] The invention relates to a composition for antisepsis, mildew prevention and preservation of corpses used in medical teaching and scientific research and a preparation method thereof. Background technique [0002] In medical teaching and scientific research, formaldehyde solution (formalin) is a traditional specimen preservation solution, which is still commonly used. Formaldehyde solution has the advantages of strong fixation and hardening effect on tissues, strong permeability, low price, strong bactericidal power, and good antiseptic effect. But practice has proved that its most obvious disadvantage is: formaldehyde has a strong pungent smell, pollutes the environment, and seriously endangers the health of anatomy teaching staff and students. Moreover, the cadaver specimens applied with formaldehyde preservation solution are highly irritating, causing students or staff members to be unable to observe the specimens carefully, which directly affects ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N1/00G09B23/28
Inventor 曹建明周铁丽楼新法杨新东刘佳明
Owner WENZHOU MEDICAL UNIV
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