Preparation method for thin coating medicine for treating cold
A film-coated tablet and Guanzhong technology, which is applied in the field of preparation of traditional Chinese medicine and western medicine composition, can solve the problems of being unable to meet the needs of different clinical conditions and the market, not giving full play to the excellent curative effect, and having no standard quality. Cost and energy consumption are reasonable and optimized, product dosage forms are enriched, and quality is controllable
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Embodiment 1
[0029] Guanzhong 320g Bupleurum 320g Daqingye 240g Honeysuckle 160g Bezoar 8g
[0030] Acetaminophen 100g Chlorpheniramine Maleate 1.2g Microcrystalline Cellulose 50g
[0031] Carboxymethyl Starch Sodium 60g Magnesium Stearate 10g
[0032] Its preparation method comprises the following steps:
[0033] 1) Take Guanzhong, Bupleurum, Daqingye, and honeysuckle, add water and decoct twice, add 10 times the amount of water for the first time, decoct for 3 hours, add 8 times the amount of water for the second time, decoct for 2 hours, use 300 Filter through a mesh filter cloth, and combine the filtrates;
[0034] 2) Concentrate the filtrate into a clear paste with a relative density of 1.20-1.25 (50-60°C) at a temperature of 70-80°C and a vacuum of 0.08-0.1Mpa. Dry under the condition of 0.08~0.1Mpa, crush into fine powder, add bezoar powder, acetaminophen, chlorpheniramine maleate, microcrystalline cellulose, sodium carboxymethyl starch and mix well;
[0035]3) Granulate with 70...
Embodiment 2
[0040] Guanzhong 320g Bupleurum 320g Daqingye 240g Honeysuckle 160g Artificial Bezoar 8g
[0041] Acetaminophen 100g Chlorpheniramine Maleate 1.2g Dextrin 50g
[0042] Pregelatinized starch 60g Magnesium stearate 10g
[0043] Its preparation method comprises the following steps:
[0044] 1) Take Guanzhong, Bupleurum, Daqingye, and honeysuckle, add water and decoct twice, add 8 times the amount of water for the first time, decoct for 2 hours, add 6 times the amount of water for the second time, decoct for 1 hour, use 200 Filter through a mesh filter cloth, and combine the filtrates;
[0045] 2) Concentrate the filtrate into a clear paste with a relative density of 1.20-1.25 (50-60°C) at a temperature of 70-80°C and a vacuum of 0.08-0.1Mpa. Dry under the condition of 0.08~0.1Mpa, crush into fine powder, add artificial bezoar powder, acetaminophen, chlorpheniramine maleate, dextrin, and pregelatinized starch and mix well;
[0046] 3) Granulate with 70% ethanol, dry at a tempe...
Embodiment 3
[0051] Guanzhong 320g Bupleurum 320g Daqingye 240g Honeysuckle 160g Artificial Bezoar 8g
[0052] Acetaminophen 100g Chlorpheniramine Maleate 1.2g Microcrystalline Cellulose 40g
[0053] Starch 50g Magnesium stearate 12g
[0054] Its preparation method comprises the following steps:
[0055] 1) Take Guanzhong, Bupleurum, Daqingye, and honeysuckle, add water and decoct twice, add 12 times the amount of water for the first time, decoct for 3 hours, add 10 times the amount of water for the second time, decoct for 2 hours, use 300 Filter through a mesh filter cloth, and combine the filtrates;
[0056] 2) Concentrate the filtrate into a clear paste with a relative density of 1.20-1.25 (50-60°C) at a temperature of 70-80°C and a vacuum of 0.08-0.1Mpa. Dry under the condition of 0.08-0.1Mpa, crush into fine powder, add bezoar powder, acetaminophen, chlorpheniramine maleate, microcrystalline cellulose, and starch and mix well;
[0057] 3) Granulate with 70% ethanol, dry at a tempe...
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