Fluid composition for increased total water intake

A technology of composition and intake, applied in the direction of drug combination, application, animal feed, etc., can solve the problem of not being able to buy companion animals from the market, achieve high palatability, and increase water intake

Inactive Publication Date: 2009-06-10
HILLS PET NUTRITION INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] An existing problem is the absence of commercially available products known to treat companion animals requiring increased total water intake, wherein the product induces spontaneous water intake

Method used

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  • Fluid composition for increased total water intake
  • Fluid composition for increased total water intake
  • Fluid composition for increased total water intake

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Preparation of SAWA fluid

[0033]Frozen pork livers were ground through a 1 / 8" plate. 200 lbs of ground pork livers were placed in a 300 lb capacity jug. 20 lbs of water was added to the jug and the mixture was heated to 145°F. Add 181.6g of ENZECO-AS-L (fungal protease from Enzyme Development Co.) to the mixture. Then keep the mixture at 145°F for 1 hour, then heat to 160°F. Add 181.6g of Papain 6000 (Plant Protease available from Valley Research, Inc.). The mixture was heated to 195°F and maintained at this temperature for 15 minutes. The mixture was then cooled to 100°F and filtered through a #20 mesh (US mesh). Collect The portion that passed the sieve was used as the "palatability enhancer" fraction. The palatability enhancer was then added to deionized water to form an aqueous mixture containing 5% by weight of the palatability enhancer. The deionized water and palatability enhancer The reagents were combined in an APV mixing vessel and mixed for 30 minutes. The...

Embodiment 2

[0035] cat studies

[0036] The SAWA prepared in Example 1 was tested in eight adult cats fed a commercial maintenance dry cat food. Total water intake, total urine output and urine specific gravity were measured for each study group. A crossover study design was used. The cats were randomly divided into two groups of four cats each. One group was supplied with drinking water contained in two plastic bottles, each containing about 500 g of drinking water (control group). Another group was supplied with drinking water and SAWA in two plastic bottles, one containing about 500 g of drinking water and the other containing about 500 g of SAWA (SAWA group). After two weeks, the control and SAWA groups were crossed over and treated accordingly for an additional two weeks. Water intake and urine output were measured daily during the two- and four-week study period. The total water intake of the control group was measured as the sum of water intake from drinking water and water fr...

Embodiment 3

[0042] Studies of cats using comparative products

[0043] This study compared the efficacy of SAWA from Example 1 and a commercially available product formulated and sold as a pet drink. SAWA compared to commercially available substances including Feline / Canine Veterinary Diet TM Rehydration Support TM , and from canned Brand large light tuna (light tuna) tuna juice (the balance is water). The tuna juice was diluted with water such that the nitrogen concentration of the diluted tuna juice was similar to that in SAWA.

[0044] A crossover study design similar to that in Example 2 was used. The 2 groups in Example 2 are replaced by the current 4 groups. They are control group (drinking water group), SAWA group, Feline / Canine Veterinary Diet TM Rehydration Support TM group and diluted tuna juice group. Eight cats were fed maintenance dry cat food. This test method follows the method of Example 2, replacing the SAWA of Example 2 with each product. The results of...

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Abstract

The present invention provides a highly palatable fluid composition for oral consumption that contains liver digestate and increases total water intake and urine production and reduces urine specific gravity in a companion animal. The invention also provides methods of using these compositions to increase the total water intake of a companion animal.

Description

[0001] Cross References to Related Applications [0002] This application is a non-provisional application of US Provisional Application 60 / 518,555 filed November 7, 2003, the contents of which are incorporated by reference in their entirety for all purposes. technical field [0003] The present invention provides palatable fluid compositions that increase total water intake. Background technique [0004] Dogs and cats suffer from a variety of lower urinary tract disorders, especially idiopathic uropathy, crystalluria, bacterial cystitis, urolithiasis, idiopathic obstruction, urethral embolism, etc. A particular condition is lower urinary tract disease (LUTD), which is common in cats. Urolithiasis, the formation of stones in the urinary tract, is a common condition in both dogs and cats. Although the etiology of these disorders is not fully understood, at least some of the factors associated with these disorders appear to be due to concentrated urine, ie urine with a high ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N45/00A23K1/10A23K1/165A23K1/18A23K50/15A61K35/407
CPCA23K1/1846A23K1/1866A23K1/1853A23K1/106A23K10/26A23K50/40A23K50/42A23K50/48A61P7/10A61P13/00A61P13/02A61P43/00
Inventor S·于C·F·-F·林C·A·柯克
Owner HILLS PET NUTRITION INC
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