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Medical composition for inhibiting the growth of cancer stem cell

a technology of stem cells and medicine compositions, which is applied in the direction of biocide, plant/algae/fungi/lichens, biocide compositions, etc., can solve the problems of stressing side effects on patients, thorny problems, and chemotherapeutic drugs nowadays can kill only common cancer cells, so as to inhibit the growth of common cancer cells and inhibit the growth of cancer stem cells

Inactive Publication Date: 2011-07-28
NATIONAL TAIWAN NORMAL UNIVERSITY +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0009]The object of the present invention is to provide a medical composition capable of inhibiting growth of cancer stem cells. Also, the medical composition according to the present invention can inhibit growth of common cancer cells.

Problems solved by technology

The main factor causing cancer is that cells become abnormal and keep dividing to form more cells, resulting in cancer.
Western medicine therapy for treatment of cancer, such as surgery, radiation therapy, chemotherapy, hormone therapy and biopharmaceutical therapy, is notorious for the distressing side-effects on patients.
The aforementioned fact is a thorny problem in treating cancer.
The Western chemotherapeutic drugs nowadays can kill only common cancer cells, and cannot efficiently inhibit growth of cancer stem cells.
Although some clinical treatment results suggest that parts of medical compositions for treating cancer cells are indeed capable of controlling cancer, the efficiency of these medical compositions in inhibiting cancer cells as well as cancer stem cells has not been confirmed.

Method used

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  • Medical composition for inhibiting the growth of cancer stem cell
  • Medical composition for inhibiting the growth of cancer stem cell
  • Medical composition for inhibiting the growth of cancer stem cell

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0028]Coptis chinensis (10 g), Scutellaria baicalensis (10 g), Phellodendron amourense (10 g), Gardenia jasminoides (10 g), Radix Glycyrrhizae (10 g), and Atractylodes japonica (10 g) are cut into slices and mixed with water to perform heating and extraction to obtain an extract. Herein, the heating is performed for 90 minutes at 70° C. Accordingly, the resulting extract is the medical composition according to the present example.

example 2

[0041]Coptis chinensis (10 g), Rhizoma cumicifugae (10 g), Angelica sinensis (10 g), Rhizome of rehamnnia (10 g) and Cortex Moutan Radicis (10 g) are cut into slices and mixed with water to perform heating and extraction to obtain an extract. Herein, the heating is performed for 90 minutes at 70° C. Accordingly, the resulting extract is the medical composition according to the present example.

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PUM

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Abstract

A medical composition for inhibiting the growth of cancer stem cells is disclosed. The medical composition is prepared by mixing herbal medicines with water or alcohol, followed by heating and extraction to obtain a filtrate. One of the medical compositions according to the present invention includes: Coptis chinensis, Scutellaria baicalensis, Phellodendron amourense, Gardenia jasminoides, Radix Glycyrrhizae, and Atractylodes japonica.

Description

BACKGROUND OF THE INVENTION[0001]1. Field of the Invention[0002]The present invention relates to a medical composition for inhibiting the growth of cancer stem cells, which is capable of inhibiting the growth of cancer stem cells in addition to common cancer cells.[0003]2. Description of Related Art[0004]Cancer has always been one of ten leading causes of death but has increased in its perniciousness to become the first cause of death for 27 years. The main factor causing cancer is that cells become abnormal and keep dividing to form more cells, resulting in cancer.[0005]Western medicine therapy for treatment of cancer, such as surgery, radiation therapy, chemotherapy, hormone therapy and biopharmaceutical therapy, is notorious for the distressing side-effects on patients. In view of those difficulties, more and more people opt for the less-radical Chinese medicine therapy. However, for both Chinese and Western medicine therapy, the commercial anticancer drugs can inhibit only growt...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K36/718A61P35/00
CPCA61K36/232A61K36/284A61K36/484A61K36/539A61K36/65A61K36/71A61K36/718A61K36/804A61K36/756A61K36/744A61K2300/00A61P35/00
Inventor HSIEH, HSIU-MEILEE, CHEN-YU
Owner NATIONAL TAIWAN NORMAL UNIVERSITY
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