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Photoprotector and/or photoimmunoprotector compositions of the skin and their uses

a technology of photoprotectors and compositions, applied in the field of photoprotectors and/or photoimmunoprotector compositions of the skin, can solve the problems of induction of cell death, damage to epidermal and dermal cells, and uncontrolled exposure to solar radiation and ultraviolet radiation coming from artificial lamps, so as to prevent or minimise the damage produced by uv

Inactive Publication Date: 2007-02-01
IND FARM CANTABRIA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0007] The invention addresses the problem of providing an efficient composition to prevent or minimise the damaging effects produced by UV radiation on the skin.
[0009] Therefore, in one aspect, the invention is associated with a photoprotector and / or photoimmunoprotector composition suitable for preventing or minimising the damaging effects produced by UV radiation on the skin. The aforementioned composition can be used in the preparation of pharmaceutical or cosmetic compositions, as well as food supplements used in the preparation of functional foods.
[0012] In another aspect, the invention is associated with the use of the aforementioned photoprotector and / or photoimmunoprotector composition in the preparation of a drug or pharmaceutical composition to prevent or minimise the damaging effects produced by UV radiation on the skin.

Problems solved by technology

In fact, numerous scientific studies suggest that the uncontrolled exposure to solar radiation and ultraviolet radiation coming from artificial lamps is harmful to the human skin and produce burns, damage to the epidermal and dermal cells, induction of cell death, changes in pigmentation, immunosuppression, premature ageing, and, eventually, skin cancer (Young A R. Chronic effects of ultraviolet radiation on the skin.

Method used

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  • Photoprotector and/or photoimmunoprotector compositions of the skin and their uses
  • Photoprotector and/or photoimmunoprotector compositions of the skin and their uses
  • Photoprotector and/or photoimmunoprotector compositions of the skin and their uses

Examples

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example 1

[0141] Photo (Immune) Protector Compositions and Their Properties [0142] 1.1 Photo (Immune) Protector Compositions

[0143] The compositions I-VI which are shown in Table 1 are prepared by means of measuring and mixing of the different compounds up to homogenisation, adjusting the pH to the values indicated by means of the addition of sodium hydroxide.

TABLE 1Prepared compositionsComponentIIIIIIIVVVIA4-hydroxybenzoic0.128 g0.128 g0.128 g—0.128 g—acidA3,4-0.112 g0.112 g0.112 g0.112 g0.112 g0.112 gdihydroxybenzoicacidA3-methoxy-4-0.096 g0.096 g0.096 g0.096 g0.096 g0.096 ghydroxybenzoicacidA4-hydroxycinamic0.096 g0.096 g0.096 g0.096 g0.096 g0.096 gacidA3,4-0.096 g0.096 g0.112 g0.096 g0.096 g0.096 gdihydroxycinamicacidA3-methoxy-4-0.016 g0.016 g0.033 g0.106 g——hydroxycinamicacidAChlorogenic acid0.006 g0.006 g—0.223 g 0.06 g0.223 gAAmide of 3,4-— 0.1 g————dihydroxycinamicacidBQuinic acida0.150 g0.150 g0.200 g0.130 g0.150 g0.130 gCCurcumin————0.032 g0.201 gpHb5.56.55.56.55.56.5Administrati...

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Abstract

The composition comprises of a component A selected from a hydroxylated derivative of benzoic acid or of cinamic acid, their esters, amides or salts, a glycoside of a hexose, and their mixtures; and a component B selected from quinic acid, shikimic acid, their alkaline metal or alkaline earth salts, their methyl esters, and mixtures of the same. This composition is suitable for protecting the skin against ultraviolet radiation coming from the sun or artificial sources, such as those used in phototherapy units and in sun tanning rooms. For application in the field of dermatology and nutrition, and, in particular, in the photoprotection of the skin and mucosa, photo-ageing and photocarcinogenesis, including protection of the immune system associated with the skin.

Description

FIELD OF THE INVENTION [0001] In general, the invention is related to the field of dermatology and photobiology, and, in particular, to the area of photoprotection of the skin and mucosa, including the protection of the immune system associated with the skin. More specifically, the invention is related to a suitable composition to protect the skin against ultraviolet radiation coming from the sun or artificial sources, such as those used in phototherapy units and in sun tanning rooms. HISTORY OF THE INVENTION [0002] It is becoming increasingly evident that a large number of diseases of the skin are a result of the interaction of ultraviolet (UV) (290-400 nm) and visible (vis) (400-700 nm) radiation on the skin (Gonzalez E, Gonzalez S. Drug photosensitivity, idiopathic photodermatoses and sunscreens. J Am Acad Dermatol 1996; 35: 871-85). In fact, numerous scientific studies suggest that the uncontrolled exposure to solar radiation and ultraviolet radiation coming from artificial lamp...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K8/37A61K31/7024A61K31/235A61K8/365A61K8/368A61K8/60A61Q17/04
CPCA61K8/365A61K8/678A61K8/37A61K8/602A61K31/192A61K31/216A61K31/315A61K31/7024A61Q17/04A61K8/368A61K8/60A61K8/36A61K8/35A61K2300/00
Inventor GUERRERO GOMEZ-PAMO, ANTONIODOMINGUEZ VALDES-HEVIA, MARTABRIEVA DELGADO, AURORA MAGARCIA MARTINEZ, FERNANDOALONSO LEBRERO, JOSE LUISGONZALEZ RODRIGUEZ, SALVADORPIVEL RAVIERY, JUAN PABLOPATHAK, MADHUKAR A.
Owner IND FARM CANTABRIA
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