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Injection of compound aminophylline for animal use, and preparation method

A technology for compound aminophylline and injection, which can be applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc. The effect of expanding the antibacterial spectrum

Inactive Publication Date: 2006-12-06
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For decades, ofloxacin has been listed as the first-choice drug for the treatment of porcine respiratory diseases. Due to long-term and repeated use of antibiotics, the body has developed tolerance to the drug, reducing the curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] First take 20g of water and heat it to 60°C, add 3g of houttuyfonate sodium, and stir to dissolve. Then take 20g of water and heat it to 60°C, add 10g of aminophylline and stir, add 1.3g of ethylenediamine and stir to dissolve the aminophylline. Mix the solutions prepared in the above two steps, add 1.5 g of benzyl alcohol and stir evenly, adjust the pH to 8.0-9.6, and add water for injection to 1000 ml.

Embodiment 2

[0023] First take 25g of water and heat it to 70°C, add 3g of houttuyfonate sodium, and stir to dissolve. Then take 30g of water and heat it to 70°C, add 10g of aminophylline and stir, add 1g of ethylenediamine and stir to dissolve the aminophylline. Mix the solutions prepared in the above two steps, add 1 g of benzyl alcohol and stir evenly, adjust the pH to 8.0-9.6, and add water for injection to 1000 ml.

Embodiment 3

[0025] First take 30g of water and heat it to 80°C, add 2g of houttuyfonate sodium, and stir to dissolve. Then take 40g of water and heat it to 80°C, add 5g of aminophylline and stir, add 2g of ethylenediamine and stir to dissolve the aminophylline. Mix the solutions prepared in the above two steps, add 2 g of benzyl alcohol and stir evenly, adjust the pH to 8.0-9.6, and add water for injection to 1000 ml.

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PUM

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Abstract

A veterinary compound injection of euphyllin for treating asthma, pneumonia, infectious pleural pneumonia, bronchial pneumonia, atrophic rhinitis, etc of pig is prepared through dissolving sodium houttuyfonate in hot water at 60-90 deg.C, dissolving euphyllin and ethyldiamine in hot water at 60-90 deg.C, mixing them together, adding phenylmethanol, stirring, and adding the water for injection.

Description

technical field [0001] The invention relates to a chemical drug composition and a preparation method, in particular to a compound aminophylline injection and a preparation method thereof. Background technique [0002] Porcine respiratory disease is one of the most common diseases in pig herds, which seriously restricts the development of pig industry. For decades, ofloxacin has been listed as the first-choice drug for the treatment of porcine respiratory diseases. Due to long-term and repeated use of antibiotics, the body develops tolerance to the drug, which reduces the curative effect. Contents of the invention [0003] The object of the present invention is to overcome above-mentioned shortcoming, improve curative effect, provide a kind of veterinary compound aminophylline injection that avoids body toleration. [0004] A kind of veterinary compound aminophylline injection of the present invention is made by following method: [0005] (1) Take 20-50 parts by weight of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/522A61K31/121A61K9/08A61K47/18A61K47/10A61P31/04A61P11/00
Inventor 魏宗生郭建华
Owner TIANJIN SHENGJI GRP CO LTD
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