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Medical hemostasis anti-adhesive irrigation solution

A rinsing solution and anti-adhesion technology, applied in the field of polymer biomaterial irrigating solution, can solve the problems of inability to inhibit implantation transfer, ineffective antibacterial, hemostasis, etc., and achieve rapid healing, prevention of implantation transfer, and growth inhibition. Effect

Inactive Publication Date: 2006-10-25
胡军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The flushing solution currently used clinically is traditional normal saline, which can neither effectively antibacterial, stop bleeding, prevent tissue adhesion, promote wound healing, nor inhibit implantation metastasis due to adhesion of scattered tumor cells during surgery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0049] Raw material: non-water-soluble chitosan 0.5%

[0050] Sodium chloride 0.75%

[0051] Water for Injection 98.75%

[0052] Preparation:

[0053] 1. Dissolve non-water-soluble chitosan in dilute acetic acid solution (add glacial acetic acid of 1 ml per 100 ml of water for injection) to obtain solution (1), set aside;

[0054] 2. Sodium chloride is dissolved in water for injection to prepare solution (2);

[0055] 3. Mix the above two solutions, add 0.1% activated carbon, heat and boil for 30 minutes, and then add water for injection to a sufficient amount;

[0056] 4. Suction filtration, fine filtration, aseptic filling, and high-pressure steam sterilization at 115° C. for 30 minutes to obtain the finished product.

example 2

[0058] Raw material: water-soluble chitosan 0.5%

[0059] Sodium chloride 0.75%

[0060] Water for Injection 98.75%

[0061] Preparation:

[0062] 1. Dissolve the water-soluble chitosan in water for injection to obtain solution (1), and set aside;

[0063]2. Sodium chloride is dissolved in water for injection to prepare solution (2);

[0064] 3. Mix the above two solutions, add 0.1% activated carbon, heat and boil for 30 minutes, and then add water for injection to a sufficient amount;

[0065] 4. Suction filtration, fine filtration, aseptic filling, and high-pressure steam sterilization at 115° C. for 30 minutes to obtain the finished product.

Embodiment 3

[0067] Raw material: carboxymethyl chitosan 0.5%

[0068] Sodium chloride 0.75%

[0069] Water for Injection 98.75%

[0070] Preparation:

[0071] 1. Carboxymethyl chitosan is dissolved in water for injection to obtain solution (1), which is set aside;

[0072] 2. Sodium chloride is dissolved in water for injection to prepare solution (2);

[0073] 3. Mix the above two solutions, add 0.1% activated carbon, heat and boil for 30 minutes, and then add water for injection to a sufficient amount;

[0074] 4. Suction filtration, fine filtration, aseptic filling, and high-pressure steam sterilization at 115° C. for 30 minutes to obtain the finished product.

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PUM

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Abstract

The present invention relates to medical hemostatic adhesion-resisting irrigating solution for operation period. It is made up by using injection water as carrier, using non-water-soluble chitosan or water-soluble chitosan or carboxymethyl chitosan as main raw material and adding NaCL or mannilol or glycine as auxiliary material through a certain preparation process.

Description

technical field [0001] The invention relates to a surgical perioperative flushing solution, in particular to a polymer biomaterial flushing fluid used in surgical perioperatives that can stop bleeding, antibacterial and prevent postoperative tissue adhesion. Background technique [0002] Irrigate fluids are used throughout surgical procedures to irrigate open surgical wounds. The flushing solution currently used clinically is traditional normal saline, which can neither effectively antibacterial, stop bleeding, prevent tissue adhesion, promote wound healing, nor inhibit implantation metastasis due to adhesion of scattered tumor cells during surgery. Contents of the invention [0003] The purpose of the present invention is to provide a hemostatic anti-adhesion flushing solution used in perioperative surgery, which can reduce tissue adhesion after surgery, has hemostasis, antibacterial, and promotes wound healing, thereby redu...

Claims

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Application Information

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IPC IPC(8): A61K31/722A61P41/00
CPCY02A50/30
Inventor 胡军仝俊太鄂云祥
Owner 胡军
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