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Cinese medicine increasing leucocyte and preparation thereof

A technology of white blood cells and production methods, which can be applied in pharmaceutical formulations, extracellular fluid diseases, medical preparations containing active ingredients, etc. Immunity, hematopoietic enhancement, elimination of anemia and bleeding symptoms

Inactive Publication Date: 2003-04-02
成海荣
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AI Technical Summary

Problems solved by technology

[0003] Leukopenia caused by radiotherapy and chemotherapy can lead to severe infection and even death. For this serious consequence, CSF (genetic recombinant granulocyte colony-stimulating factor) is usually used clinically to promote the differentiation and proliferation of hematopoietic granulocytes and stimulate the growth and release of granulocytes. Increase the granulocytes in the peripheral blood, prevent and treat severe infections, and reduce the mortality rate. The use of CSF has a reliable curative effect, but has the following disadvantages: 1) For M 3 2) It has certain side effects, such as allergies and cannot be used; 3) It is an injection type in use, which will bring pain to patients; 4) Most scholars believe that people with uncontrolled leukemia should not use it because CSF It also has a growth-promoting effect on the immature white blood cells of leukemia patients, which can cause leukemia recurrence or aggravate the disease

Method used

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Embodiment Construction

[0011] By weight, take 100 grams of ginseng, 500 grams of atractylodes, 500 grams of rice vinegar, and 900 grams of alum. , crushed into granules below 120 mesh, and then mixed with the aforementioned granules.

[0012] The above-mentioned traditional Chinese medicine is made into honeyed pills, tablets or capsules, so that each honeyed pill, tablet or capsule contains 525 mg of the above-mentioned medicinal powder, and then packed.

[0013] Animal experiments conducted by the Chinese University of Hong Kong: mice were fed 5 mg of "Shen Bailing" every day, and after three days, the expression characteristics of mRNA (information nucleic acid) in spleen cells of different mice were measured. The results found that: the interleukin-1 -alpha (1L-1 alpha) was four times higher than the control group, interleukin 13 (1L-13) was three times higher than the control group, and stem cell factor (SCF) was two times higher than the control group.

[0014] The biological activity of inte...

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Abstract

A Chinese medicine for promoting the regeneration of white cell and treating the leukocytopenia caused by chemicotherphy or radiotherapy is prepared from ginseng, atractylodes rhizome, rice vinegar and green alum through baking and pulverizing ginseng and atractylodes rhizome to obtain particles less than 120 meshes, mixing, calcining and pulverizing others to obtain particles less than 12 meshes, and mixing. Its advantages are high curative effect and no toxic by-effect.

Description

technical field [0001] The invention belongs to the class of traditional Chinese medicines, and specifically relates to a traditional Chinese medicine (Shen Bai Ling) and a manufacturing method for treating leukopenia and agranulocytosis caused by radiotherapy and chemotherapy. Background technique [0002] Radiotherapy and chemotherapy, as one of the main methods for treating malignant tumors, have long been recognized by the medical community. However, the severe side effects brought about by radiotherapy and chemotherapy, such as nausea and vomiting, anorexia, oral and esophageal ulcers, etc., make patients unbearable and persistent, especially leukopenia and agranulocytosis caused by radiotherapy and chemotherapy. Serious toxic and side effects have not been resolved so far, and patients are often forced to stop the course of radiotherapy and chemotherapy, which greatly affects the curative effect and the patient's survival time. How to promote the incre...

Claims

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Application Information

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IPC IPC(8): A61P7/00
Inventor 成碧春成海荣
Owner 成海荣
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