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Wolfberry polysaccharide and its prepn. and application

A technology of Lycium barbarum polysaccharide and Lycium barbarum, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, organic active ingredients, etc., can solve the problems of reduced pharmacological effects and no pharmacological effects, and achieves clear active ingredients, no adverse reactions, and curative effects. reliable results

Inactive Publication Date: 2003-01-08
张平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to research reports, Lycium barbarum polysaccharides with obvious pharmacological effects have a molecular weight of more than 10,000, while Lycium barbarum monosaccharides and oligosaccharides are considered to have no pharmacological effects. If the polysaccharides are separated too purely, the pharmacological effects will be significantly reduced. Phenomenon

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Take 1000g of medlar, after sorting, rinse it with normal water, put it in a container, add 15 times of hot water at 80°C, cut it with a high-speed shear for 30 minutes, squeeze it, take the squeezed juice and centrifuge it at high speed, and the centrifugate Filtrate with an ultrafiltration membrane with a molecular weight cutoff of 50,000 to 100,000, concentrate the ultrafiltrate with an ultrafiltration membrane with a molecular weight cutoff of 3,000 to 10,000, and freeze-dry to obtain the product. Example 2 Preparation of Lycium barbarum polysaccharide oral liquid

Embodiment 2

[0015] Take 1000g of medlar, after sorting, rinse it with normal water, put it in a container, add 15 times of hot water at 80°C, cut it with a high-speed shear for 30 minutes, squeeze it, take the squeezed juice and centrifuge it at high speed, and the centrifugate Filtrate with an ultrafiltration membrane with a molecular weight cutoff of 50,000 to 100,000, concentrate the ultrafiltrate with an ultrafiltration membrane with a molecular weight cutoff of 3,000 to 10,000, and freeze-dry to obtain the product. Example 2 Preparation of Lycium barbarum polysaccharide oral liquid

[0016] Example 1 Lycium barbarum polysaccharide 50g

[0017] Sodium Benzoate 2g

[0018] Take Lycium barbarum polysaccharide from Example 1, add sodium benzoate, add water for injection to an appropriate amount, heat to dissolve, let cool, add water for injection to 1000ml, stir, filter with 0.45μl microporous membrane, fill, seal, 100°C, 30 It can be sterilized in minutes. Example 3 Preparation of wo...

Embodiment 3

[0018] Take Lycium barbarum polysaccharide from Example 1, add sodium benzoate, add water for injection to an appropriate amount, heat to dissolve, let cool, add water for injection to 1000ml, stir, filter with 0.45μl microporous membrane, fill, seal, 100°C, 30 It can be sterilized in minutes. Example 3 Preparation of wolfberry polysaccharide powder injection

[0019] Embodiment 1 Lycium barbarum polysaccharide 100g

[0020] Mannitol 50g

[0021] Take wolfberry polysaccharide, add water to mannitol, add water for injection to an appropriate amount, heat to dissolve, let cool, add water for injection to 1000ml, stir, filter with 0.22μl microporous membrane, pack in vials, freeze-dry, press Cover, seal, and serve. Example 4 Preparation of Lycium Barbarum Polysaccharide Injection

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PUM

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Abstract

The invention discloses a kind of polyose of lycium chinensis. The composition and proportion of the components of the active polyose that it contains are as follows: molecular weight 100,000-180,000:18,000-80,000:3,000-8,000 and corresponding proportion: 4-20%:8-40%:4-20%. The preparing method is as follows: use of lycium chinensis as raw material, add 8-20 times hot water of 50-100 centigrade to it, then use the high-speed cutter to cut it for 10-40 minutes, then press it, extract the juice pressed from it to high-speedily centrifugate the juice, then use the ultra-filtration membrane which can hold back the molecules whose molecular weight is 5-100,000 to filter the centrifugal juice, then use the ultra-filtration membrane which can hold back the molecules whose molecular weight is 3,000-10,000 to condense the ultra-filtration liquid.

Description

Technical field [0001] The invention relates to a wolfberry polysaccharide, and at the same time, the invention also relates to a preparation method of the wolfberry polysaccharide and its application in treating diseases caused by low immunity. Background technique [0002] The main active ingredient in Lycium barbarum is polysaccharides, its main effect can improve the body's immunity, so it can be used to treat diseases caused by low immunity, such as long-term colds, asthma, cancer, etc. The carbohydrates in Lycium barbarum are mostly monosaccharides and oligosaccharides, and the content of polysaccharides is relatively small. In the previous polysaccharide extraction process, there are many long-term high-heat extraction processes, such as decoction and concentration, which will not only deepen the color of the final product, but also break many polysaccharides into oligosaccharides and monosaccharides. According to research reports, Lycium barbarum polysaccharides wit...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61P37/04C08B37/00
Inventor 张平
Owner 张平
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