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Fucoidin ester as antiviral immunoregulator and its prepn

A technology of fucoidan esters and immunomodulators, which is applied in the field of new seaweed biological drugs and its preparation, can solve the problems of low yield, achieve high yield, low process cost, and reduce the residue of impurities

Inactive Publication Date: 2002-04-17
汤洁 +1
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Problems solved by technology

[0002] The raw materials involved in the present invention are brown algae, mainly kelp (i.e. Laminaria Japomica) artificially cultivated in my country, and wild brown algae and Sargassum (Sorgassum) with the largest output in my country can also be used. In addition to containing alginate which is widely used in industry, It also contains fucoidin. So far, the brown algae industry in my country is limited to the extraction of alginate. The extraction of fucoidin is limited to the laborator

Method used

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  • Fucoidin ester as antiviral immunoregulator and its prepn

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preparation example

[0048] 1) Pretreatment of seaweed:

[0049] Dried seaweed (moisture content 14%-30%) is crushed into 1×1cm pieces, sieved, and air-selected to remove impurities. With dry treatment, seaweed can save a lot of water for soaking and cleaning, which is beneficial to environmental protection and water saving, and is convenient for transportation, storage and operation. This step is completed in the original place of seaweed.

[0050] 2) Stirring and extraction under temperature control:

[0051] Add part of the concentrated condensed water and RO separated water to the pretreated seaweed, then add tap water, then mechanically stir at 55°C, and extract for 2 hours, so that the extraction rate of fucoidan can reach more than 85%. The lowest content of alginic acid in the extract is used for further separation and purification.

[0052] 3) Centrifugal separation:

[0053] The extract is centrifuged to separate the residue, and the residue can be directly used in the production and di...

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Abstract

The present invention is serial antiviral immunoregulators, including feed additive for fish, shrimp and pet; immunoregulator vaccine for farm animal and antiviral injection for farm animal and pet, with fucoidin ester as effective component. During its preparation, fucoidin ester is first extracted from kelp and other brown algae through the steps of lixiviation, centrifugal separation, reverse osmosis to cencentrate, ethanol, precipitation, active carbon decoloring, ultrafiltering to desalt and refining, and then further prepared into the antiviral immunoregulator through superfine crushing, vacuum drying and other technological steps. The technological process is simple, high yield, high purity and easy to realize in industrial production.

Description

technical field [0001] The invention relates to a new seaweed biological drug and a preparation method thereof-the preparation method of fucoidan ester as an antiviral and immune regulator, belonging to the technical field of seaweed biochemistry. technical background [0002] The raw materials involved in the present invention are brown algae, mainly kelp (i.e. Laminaria Japomica) artificially cultivated in my country, and wild brown algae and Sargassum (Sorgassum) with the largest output in my country can also be used. In addition to containing alginate which is widely used in industry, It also contains fucoidin. So far, the brown algae industry in my country is limited to the extraction of alginate. The extraction of fucoidin is limited to the laboratory preparation stage. Some industrial extraction methods of fucoidin have a high yield. Very low, for example Chinese Patent Publication No. CN1129109A fucoidan sulfate is used as medicine for treating renal failure and vascul...

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Application Information

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IPC IPC(8): A61K47/36A61P37/02
Inventor 汤洁王为璋
Owner 汤洁
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