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Medicine for resolving sputum and relieving asthma and cough, preparing process thereof

A technology for relieving cough and asthma, and a preparation process, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, can solve problems such as large side effects, slow effects, and unsatisfactory effects, and achieves rapid onset of action and small dosage. , the effect of color stability

Inactive Publication Date: 2005-08-24
JIANGSU SIMCERE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although there are many treatment methods for cough and asthma, none of them are ideal. Most of them are treated with cough relieving, asthma relieving, and phlegm resolving, and generally Western medicine is the main treatment, and it has a single effect, such as codeine phosphate for relieving cough and theophylline for relieving asthma. , ammonium chloride to reduce phlegm, etc., but these drugs have large side effects, slow effect, and easy recurrence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Embodiment 1: This example is the best embodiment

[0043] Raw material formula: 1340g ephedra, 670g gypsum, 1330g bitter almond, 670g platycodon, 670g centipede, 670g poppy shell, 1330g licorice. Prepare 1000ml.

[0044] Preparation process: take gypsum powder according to the raw material formula, add water to decoct for 1 hour, filter, and use the filtrate for later use, add water to the remaining six herbs such as medicinal residues and ephedra, adjust the pH to 5, decoct twice, each time for 1.5 hours, filter separately, and combine the filtrate And the above standby medicinal solution; when concentrated to 50°C, the relative density is 1.14; let it cool, add ethanol until the alcohol content is 75%, adjust the pH value to 7.8, and filter; the filtrate recovers ethanol under reduced pressure at 50°C; add appropriate amount of auxiliary materials , add water to 1000ml, let stand at 4°C for 48 hours, filter; centrifuge the solution at 8000rpm and filter it with a 0....

Embodiment 2

[0046] Raw material formula: 1206g of ephedra, 804g of gypsum, 1474g of bitter almond, 536g of platycodon, 804g of basil, 804g of poppy shell, and 1474g of licorice. Prepare 1000ml.

[0047] Preparation process: take gypsum powder according to the raw material formula, add water to decoct for 1 hour, filter, and use the filtrate for later use, add water to the remaining six herbs such as medicinal residues and ephedra, adjust the pH to 5, decoct twice, each time for 1.5 hours, filter separately, and combine the filtrate And the above standby medicinal solution; when concentrated to 50°C, the relative density is 1.14; let it cool, add ethanol until the alcohol content is 75%, adjust the pH value to 8.0; filter, and recover the ethanol from the filtrate under reduced pressure at 50°C; add appropriate amount of auxiliary materials , add water to 1000ml, let it stand at 4°C for 48 hours, filter; centrifuge the solution at 5000rpm at high speed; potting, sterilization, visual inspect...

Embodiment 3

[0049] Raw material formula: 1474g of ephedra, 536g of gypsum, 1206g of bitter almond, 804g of platycodon, 804g of basil, 536g of poppy shell, and 1206g of licorice. Prepare 1000ml.

[0050] Preparation process: take gypsum according to the raw material formula, add water and decoct for 1 hour, filter, and the filtrate is set aside, add water to the remaining six herbs such as medicinal residues and ephedra, adjust the pH to 5.1, decoct twice, each time for 1 hour, filter separately, combine the filtrate and The above standby filtrate; the relative density when concentrated to 50°C is 1.14; let it cool, add ethanol until the alcohol content is 75%, adjust the pH to 7.9, and filter; the filtrate recovers ethanol under reduced pressure at 50°C; add appropriate amount of auxiliary materials, add water to 1000ml, stand at 2°C for 48 hours, filter; centrifuge at 6000rpm and filter with 0.65μm filter membrane; potting, sterilization, visual inspection, packaging.

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PUM

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Abstract

A Chinese medicine for treating cough and asthms and dispelling phlem is prepared from 7 Chinese-medicinal materials including ephedra, gpysum, bitter apricot kernel, liquorice root, etc through decocting gypsum powder, filtering to obtain its filtrate, decocting its dregs and others and filtering twice, collecting filtrate, concentrating, depositing in alcohol, regulating pH value, filtering, depositing in water, membrane filtering, and sterilizing. Its advantages are high curative effect, quickly taking its effect, and no by-effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and in particular relates to a medicine for relieving cough, relieving asthma and reducing phlegm and a preparation process thereof. Background technique [0002] Cough and asthma are common and frequently-occurring diseases, mainly manifested as cough, wheezing, chest tightness, and severe cases lead to rapid heart rate and dyspnea. Especially the elderly and children have a high incidence. [0003] Although there are many treatment methods for cough and asthma, none of them are ideal. Most of them are treated with cough relieving, asthma relieving, and phlegm resolving, and generally Western medicine is the main treatment, and it has a single effect, such as codeine phosphate for relieving cough and theophylline for relieving asthma. , ammonium chloride for resolving phlegm, etc., but these drugs have large side effects, slow effect, and are prone to relapse. Contents of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/06A61P11/06A61P11/10A61P11/14
Inventor 周进东刘武罗兴洪吴海峰
Owner JIANGSU SIMCERE PHARMA
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