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Nucleic acid detection system and nucleic acid detection instrument

A detection system and nucleic acid technology, applied in the field of biomedicine, can solve problems such as low detection efficiency and poor temperature control, and achieve the effects of high safety and reliability, rapid temperature control, and improved space utilization.

Pending Publication Date: 2022-07-01
GETEIN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The application provides a nucleic acid detection system and a nucleic acid detection instrument. Using this system can effectively solve the problems of poor temperature control and low detection efficiency of existing nucleic acid detection instruments, and can realize rapid on-site nucleic acid detection of "sample in-result out". automated detection

Method used

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  • Nucleic acid detection system and nucleic acid detection instrument
  • Nucleic acid detection system and nucleic acid detection instrument
  • Nucleic acid detection system and nucleic acid detection instrument

Examples

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Effect test

Embodiment 1

[0041] see figure 1 , A nucleic acid detection system provided by this application includes a fully enclosed microfluidic chip, a chip loading platform, a thermal cycle system, an optical detection system, a user operating system and a power supply.

[0042] The chip loading platform is provided with a chip slot, and the fully enclosed microfluidic chip is fixedly loaded on the chip slot. The thermal cycle system is controlled by the user operating system, which is used for increasing and decreasing the temperature of the fully enclosed microfluidic chip. The optical detection system is used for real-time detection of the nucleic acid-amplified sample in the fully enclosed microfluidic chip, and the detection result is sent to the user operating system in real time. The power supply provides power for the thermal cycling system, the optical detection system and the user operating system.

[0043] It should be noted that, in this embodiment, the fully enclosed microfluidic ch...

Embodiment 2

[0056] see figure 2 and 3 , A nucleic acid detection system provided by this application includes more than two fully enclosed microfluidic chips, a chip loading platform, a thermal cycle system, an optical detection system, a user operating system and a power supply.

[0057] The chip loading platform is provided with more than two chip slots, the number of the chip slots is the same as the number of the fully enclosed microfluidic chips, and each of the chip slots is fixedly loaded with one of the fully enclosed microfluidic chips Microfluidic Chip. Preferably, the number of the fully enclosed microfluidic chips can be set to any number within two to one hundred, which can be specifically determined by the detection amount of the equipment and the volume of the whole machine. The thermal cycle system is controlled by the user operating system, which is used to adjust the temperature of each fully enclosed microfluidic chip fixed in the chip slot. The optical detection sy...

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Abstract

The invention relates to a nucleic acid detection system and a nucleic acid detection instrument in the field of biomedical treatment. The detection system comprises more than two totally-enclosed micro-fluidic chips, a chip loading platform, a thermal circulation system, an optical detection system and a user operation system. The totally-enclosed micro-fluidic chips are fixedly loaded on the chip loading platform, the heat circulation system is connected with the user operation system, and the heat circulation system is used for increasing and decreasing the temperature of each totally-enclosed micro-fluidic chip. And the optical detection system is used for performing real-time detection on a sample subjected to nucleic acid amplification in the totally-enclosed micro-fluidic chip and sending a detection result to the user operation system in real time. The kit has the advantages of portability, rapidness, high flux, high automation degree, no pollution, accuracy and the like, and can realize on-site rapid and automatic nucleic acid detection of'sample input-result output '.

Description

technical field [0001] The present application relates to the field of biomedical technology, and in particular, to a nucleic acid detection system and a nucleic acid detection instrument. Background technique [0002] As the genetic material of an organism, nucleic acid records the genetic information of the corresponding organism and is also a complete representation of the identity of the organism. As a molecular diagnostic technology, nucleic acid detection is a technology that directly detects biological genetic material such as DNA and RNA, including nucleic acid extraction, amplification and detection, which plays a fundamental role in microbial analysis, medical diagnosis, and timely medical treatment. . However, the nucleic acid detection process is very complex, with many steps, and requires very high testing environment, laboratory conditions and the technical level of testing personnel. Therefore, the development trend of nucleic acid detection is immediate and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/34C12M1/38C12M1/00
CPCB01L3/5027B01L7/52B01L3/50851
Inventor 汤曾勇丁永军张中刘振宇谭超
Owner GETEIN BIOTECH
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