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Stent for vascular calcification modeling and preparation method and application thereof

A technology for vascular calcification and modeling, which is applied in the field of medical devices and can solve problems such as it is difficult to simulate calcified diseased blood vessels.

Pending Publication Date: 2022-06-28
上海昕诺医学研究有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the blood vessel walls of experimental animals are smooth, the lumen is large, and the blood flow is good, so it is difficult to simulate calcified blood vessels, and how to make the blood vessels of experimental animals grow calcified lesions is also a difficult problem

Method used

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  • Stent for vascular calcification modeling and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1: A stent for modeling vascular calcification lesions

[0034] This embodiment provides a stent for modeling vascular calcification lesions, the stent for modeling vascular calcification lesions is composed of a first stent, a second stent and a third stent; the first stent is a coronary artery with a balloon a stent; the second stent and the third stent are coronary stent segments; the second stent is sleeved at the middle position of the first stent, and the second stent is locked on the first stent through deformation; The third stent is sleeved on the second stent, and the third stent is locked on the second stent through deformation; the diameter of the first stent after balloon expansion is 3 mm; the first stent The length of the second stent and the third stent is 2.25 mm after balloon expansion; the length of the second stent and the third stent is 5 mm.

Embodiment 2

[0035] Example 2: A method for preparing a stent for modeling vascular calcification lesions

[0036] This embodiment provides a method for preparing the stent for modeling vascular calcification lesions in Example 1, and the preparation method includes the following steps:

[0037] Step 1: Select a 2.25-inch long stent (30mm in length), expand the long stent and remove it from the stent balloon, cut it into 5mm segments with ophthalmic scissors, pay attention to keeping the long stent round and not deformed to obtain a second stent and the third bracket;

[0038] Step 2: Use the 3.0 bracket (30mm in length) as the first bracket, take the second bracket in step 1 and put it in the middle of the first bracket, be careful not to pull out the inner core of the guide wire of the first bracket to avoid bending; Pinch the second bracket evenly and fix it in the center of the first bracket;

[0039] Step 3: Put the first bracket in step 2 into the Y valve, and align the narrowest p...

Embodiment 3

[0042] Example 3: A vascular calcification lesion model

[0043] This example provides a vascular calcification lesion model, and the vascular calcification lesion model is a porcine coronary artery implanted with the stent for vascular calcification lesion modeling prepared in Example 2.

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Abstract

The invention relates to a stent for vascular calcification modeling and a preparation method and application thereof, and belongs to the technical field of medical instruments. The invention provides a stent for vascular calcification modeling, the stent for vascular calcification modeling comprises a first stent, a second stent and a third stent, the second stent sleeves the first stent, the diameter of the second stent is smaller than that of the first stent, the third stent sleeves the second stent, the diameter of the third stent is smaller than that of the first stent, and the diameter of the third stent is smaller than that of the first stent. The diameter of the third bracket is smaller than or equal to that of the second bracket; after being released, the stent for vascular calcification modeling shows a dog bone shape with poor middle expansion, so that an artificial 360-degree annular calcification lesion is formed, and the stent has a great application prospect in coronary atherectomy operation training.

Description

technical field [0001] The invention relates to a stent for modeling vascular calcification lesions, a preparation method and application thereof, and belongs to the technical field of medical devices. Background technique [0002] Percutaneous coronary intervention (percutaneous coronary intervention, PCI) refers to the use of transcardiac catheter technology to dredge stenotic or even occluded coronary lumen, thereby improving myocardial blood perfusion. At this stage, the commonly used transcardiac catheterization techniques in percutaneous coronary intervention mainly include percutaneous coronary balloon angioplasty, coronary stenting, rotational atherectomy, rotational atherectomy, etc. [0003] Rotational coronary atherectomy is a transcardiac catheterization technique applied to coronary calcification lesions. When using this technique to treat patients, an olive-shaped rotational atherectomy tip with diamond particles is used. According to "selective cutting" The p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G09B23/28
CPCG09B23/28
Inventor 顾芸芸
Owner 上海昕诺医学研究有限公司
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