Application of pulsatilla saponin B4 in preparation of medicine for treating or preventing hysteromyoma

A technology of Pulsatilla saponins and uterine fibroids, applied in the field of medicine, to improve the symptoms of hair loss and temperament, reduce the level of estradiol, and improve the shape of the effect

Pending Publication Date: 2022-05-27
广西馨海药业科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Pulsatillae has the functions of clearing heat, detoxifying, cooling blood, etc., but there is no report on the prevention and treatment of pulsatilla saponin B4 for uterine fibroids

Method used

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  • Application of pulsatilla saponin B4 in preparation of medicine for treating or preventing hysteromyoma
  • Application of pulsatilla saponin B4 in preparation of medicine for treating or preventing hysteromyoma
  • Application of pulsatilla saponin B4 in preparation of medicine for treating or preventing hysteromyoma

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Embodiment Construction

[0020] The present invention will be further described in detail below with reference to the accompanying drawings, so that those skilled in the art can refer to the description and implement accordingly.

[0021] It should be noted that the experimental methods described in the following embodiments are conventional methods unless otherwise specified, and the reagents and materials can be obtained from commercial sources unless otherwise specified.

[0022] 1 material

[0023] 1.1 Animals

[0024] CD (SD) rats, female, not pregnant, weighing 200-220g, purchased from Zhejiang Weitong Lihua Laboratory Animal Technology Co., Ltd., SPF grade, production license number: SCXK (Zhe) 2019-0001, certificate number: 20210624Aazz0619000227. The natural light and dark cycle of the animal breeding room, room temperature, and free access to Celsius and water for animals.

[0025] 1.2 Drugs and Reagents

[0026] Estradiol benzoate injection, 2mg / mL, Ningbo No. 2 Hormone Factory, batch n...

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Abstract

The invention discloses an application of pulsatilla saponin B4 as a unique active ingredient in preparation of a medicine for treating or preventing hysteromyoma. The pulsatilla saponin B4 disclosed by the invention has a relatively good treatment effect on hysteromyoma of a rat molded by an estrogen load method.

Description

technical field [0001] The present invention relates to the technical field of medicine. More specifically, the present invention relates to the use of Pulsatilla saponin B4 in the preparation of a medicament for treating or preventing uterine fibroids. Background technique [0002] Uterine fibroids are the most common benign tumors in the female reproductive organs and one of the most common tumors in the human body. The etiology of uterine fibroids is still unclear, and it may involve a complex interaction between cell mutations in the normal myometrium, sex hormones, and local growth factors. Uterine fibroids are benign tumors with a very small chance of malignant transformation, while uterine cancer (endometrial cancer) is a malignant tumor caused by STD infection, long-term cervical damage, skin breakage, erosion, and inflammation. There are also differences in common symptoms between the two. Symptoms of uterine fibroids are mostly manifested during menstruation, mo...

Claims

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Application Information

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IPC IPC(8): A61K31/704A61P35/00
CPCA61K31/704A61P35/00
Inventor 高红伟杨世林苑仁祎坤李笑然
Owner 广西馨海药业科技有限公司
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