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Normal-temperature mechanical perfusion device for isolated heart

A heart and normal temperature technology, applied in the field of medical devices, can solve the problems of good cardiac normal temperature mechanical perfusion equipment, etc., to achieve the effect of maintaining a stable internal environment and improving the survival rate

Pending Publication Date: 2022-05-20
THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no good cardiac normal temperature mechanical perfusion equipment

Method used

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  • Normal-temperature mechanical perfusion device for isolated heart
  • Normal-temperature mechanical perfusion device for isolated heart
  • Normal-temperature mechanical perfusion device for isolated heart

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Experimental program
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Effect test

Embodiment Construction

[0025] Below in conjunction with accompanying drawing and specific embodiment, general scheme of the present invention is described in further detail:

[0026] see figure 1 , 2 , 3, 4. The structure of the specific embodiment of the present invention includes an organ preservation box 16, a blood storage tank 20, a membrane oxygenator 27 and a heating water tank 37, and the membrane oxygenator 27 is a membrane oxygenator for membrane lungs. The blood storage tank 20 is provided with two inlet ports 18 and one outlet port 21, and the organ preservation box 16 is provided with a right ventricular drainage tube 2, a left ventricular drainage tube 6 and an aortic root perfusion tube 14, The organ preservation box 16 is respectively connected to two blood storage tank interfaces 18 through the right ventricular drainage tube 2 and the left ventricular drainage tube 6, and the membrane oxygenator 27 is provided with a membrane oxygen interface 22, a membrane lung water outlet inter...

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Abstract

The invention relates to a normal-temperature mechanical perfusion device for an isolated heart. The device comprises an organ preservation box, a blood storage tank, a membrane type oxygenator and a heating water tank, the blood storage tank is provided with two blood storage tank inlet connectors and a blood storage tank outlet connector, and a right chamber drainage tube, a left chamber drainage tube and an aorta root perfusion tube are arranged in the organ preservation box; the organ preservation box is connected with the two blood storage tank inlet connectors through the right chamber drainage tube and the left chamber drainage tube respectively, the membrane type oxygenator is provided with a membrane lung oxygen connector, a membrane lung water outlet connector, a membrane lung water inlet connector, a membrane lung hemorrhage connector and a membrane lung blood inlet connector, and the membrane lung blood inlet connector is connected with the blood storage tank outlet connector. The membrane pulmonary hemorrhage connector is connected with the organ storage box through the aorta root infusion pipe, the heating water tank is provided with a heating water tank water return connector and a heating water tank water outlet connector, the heating water tank water outlet connector is connected with the membrane pulmonary hemorrhage water inlet connector, and the heating water tank water return connector is connected with the membrane pulmonary hemorrhage water outlet connector. Oxygen and nutrition are continuously supplied to the heart in a perfusion mode, so that the normal physiological function of the heart can be maintained, and the in-vitro preservation time of the heart is prolonged.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to an isolated heart normal temperature mechanical perfusion device. Background technique [0002] Heart transplantation is an effective method for the treatment of end-stage heart disease. At present, donor hearts are preserved in an isolated environment using organ preservation liquid cold storage, but the effective storage period is only 6 hours, which greatly limits the development of heart transplantation. Cardiac normal temperature mechanical perfusion refers to perfusing normal temperature oxygenated blood to the isolated heart by mechanical perfusion to simulate the internal environment, and then realize the normal physiological function of the heart in the external environment. This method of organ preservation is expected to greatly increase the preservation time of the heart in vitro, shorten the cold ischemia time and reduce postoperative complications of transplantation. ...

Claims

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Application Information

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IPC IPC(8): A01N1/02
CPCA01N1/0247
Inventor 郑幸龙刘雯雁闫炀郭锋伟刘锋锋
Owner THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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