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Acute coronary syndrome risk assessment marker for stable coronary heart disease and application

A coronary syndrome and risk assessment technology, applied in the field of acute coronary syndrome risk assessment markers, can solve the problem of no risk assessment of acute coronary syndrome, and achieve the effect of improving prediction accuracy

Pending Publication Date: 2022-05-06
FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE
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Problems solved by technology

[0005] However, in the prior art, there is no research report on the risk assessment of acute coronary syndrome with stable coronary heart disease by studying the characteristics of intestinal flora

Method used

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  • Acute coronary syndrome risk assessment marker for stable coronary heart disease and application
  • Acute coronary syndrome risk assessment marker for stable coronary heart disease and application
  • Acute coronary syndrome risk assessment marker for stable coronary heart disease and application

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Embodiment Construction

[0108] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention more clear, the embodiments of the present invention will be further described in detail below in conjunction with the accompanying drawings. Here, the exemplary embodiments and descriptions of the present invention are used to explain the present invention, but not to limit the present invention.

[0109] As mentioned earlier, with the rapid development of various sequencing technologies such as metagenomics, massive amounts of data have also emerged. How to mine useful information from complex and redundant biological data for disease assessment, prediction, and diagnostic indicators has always been a very challenging task. With the advent of the era of big data, researchers have developed a variety of algorithms to mine relevant data in the field of life sciences, and for marker diagnostic models, machine learning algorithms have to be mentioned. Machine lear...

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Abstract

The invention discloses an acute coronary syndrome risk assessment marker for a stable coronary heart disease and application. The markers comprise intestinal flora bifidobacterium longum, streptococcus angora, companion faecalis, Kolinella aerogenes, faecalis przewalskii, bacteroides ovale, anaerocanoidea, bacteroides fragilis, bacteroides holdmann, eubacterium rectum and streptococcus salivarius. According to the invention, risk assessment prediction is carried out on the acute coronary syndrome of the stable coronary heart disease, and the prediction accuracy can be improved.

Description

technical field [0001] The invention relates to the field of biomedical technology, in particular to markers for assessing the risk of acute coronary syndrome for stable coronary heart disease and related applications. Background technique [0002] Cardiovascular disease mainly refers to coronary atherosclerotic heart disease, referred to as coronary heart disease (coronary artery disease, CAD). Heart attack is the clinical manifestation of acute coronary syndrome (acute coronary syndrome, ACS), including sudden cardiac death, myocardial infarction and unstable angina, which is the main cause of death from coronary heart disease. The pathophysiological mechanism of ACS has been recognized as coronary atherosclerotic plaque inflammatory progression to rupture, induced thrombosis caused by acute blockage of coronary arteries. At present, the mainstream view is that cardiovascular disease, including coronary heart disease, is a class of immunometabolic diseases, as well as a c...

Claims

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Application Information

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IPC IPC(8): C12Q1/14C12Q1/06C12Q1/689G16H50/30G16B30/00
CPCG16H50/30C12Q1/14C12Q1/06C12Q1/689G16B30/00G01N2800/324G01N2800/50
Inventor 杨跃进朱海波杨进刚董超然许靖
Owner FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE
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