Validation of quantitative magnetic resonance imaging protocols

A protocol and technology to be verified, applied in magnetic resonance measurement, measurement using nuclear magnetic resonance imaging system, measurement of magnetic variables, etc., can solve problems such as inability to guarantee quantitative values

Pending Publication Date: 2022-03-01
OXFORD UNIV INNOVATION LTD
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Problems solved by technology

However, this in itself does not guarantee that quantitative values ​​measured at different scanners or centers are comparable

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  • Validation of quantitative magnetic resonance imaging protocols
  • Validation of quantitative magnetic resonance imaging protocols
  • Validation of quantitative magnetic resonance imaging protocols

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[0029] While it can be considered that one way to effectively calibrate the magnetic values ​​measured by MRI scans is to measure the magnetic properties of a substance known to be magnetic (called a "phantom") and then apply some calibration factor, it is impossible to find a substance whose The magnetism is sufficiently stable and consistent over the desired range of values ​​to enable this in a cost-effective manner.

[0030] The inventors have found that, if a clinically feasible (ie, accelerated) MRI protocol is properly followed, normal values ​​are the same between various scanners and potentially allow direct comparison of pathological deviations. From MR theory, there should be a consistent relationship between the magnetism measured by the clinically feasible sequence and that measured by the reference sequence. This relationship should have a general form that is independent of the exact specification of the property being measured. However, although understanding ...

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Abstract

A verification technique for quality assurance of quantitative MRI methods compares a measured magnetism of a phantom having a range of T1 and T2 values measured by a clinically feasible acceleration protocol with a predicted value for the magnetism calculated from a set of reference T1 and T2 values measured on the phantom. The prediction is based on a relationship between a value from an acceleration protocol and a value from a reference measurement obtained by repeatedly scanning one or more moduli.

Description

technical field [0001] The present invention relates to a method of validating or quality assurance of a protocol for quantitative magnetic resonance imaging. Background technique [0002] Magnetic Resonance (MR) Imaging (MRI) has become ubiquitous as a medical imaging technique for forming images of patient anatomy and physiological processes in healthy and diseased patients. Essentially, MR images are two-dimensional displays of contrast caused by multiple magnetic differences in patient tissue. Many different types of sequences (i.e., different combinations of static and oscillating magnetic fields and RF pulses) are known and are often preprogrammed into MRI scanners in order to allow the radiographer to select the optimal sequence to detect tissue of interest in a particular patient or Abnormal organization. This traditional sequence weights multiple MR properties in a non-linear fashion and depends on the distance from the coil used to acquire the signal. In weighte...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01R33/561G01R33/58G01R33/567G01R33/44G01R33/50A61B5/055
CPCG01R33/561G01R33/58G01R33/567G01R33/448G01R33/50A61B5/055A61B6/583A61N5/1075A61N2005/1055A61N2005/1076
Inventor 张强斯特凡·皮埃切尼克康拉德·韦里斯尤利亚·安德里亚·波佩斯库瓦内萨·费雷拉
Owner OXFORD UNIV INNOVATION LTD
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