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Washing-free antibacterial hand sanitizer and preparation method thereof

A technology of hand sanitizer and extracting liquid, which is applied in the field of hand sanitizer, can solve the problems of large hand skin irritation and limited bactericidal effect, and achieve the effect of excellent sterilizing and disinfecting effect, good biocompatibility, and enhanced phagocytosis

Active Publication Date: 2022-02-11
SHANDONG ZHONGDA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Some of the existing disposable hand sanitizers have good sterilization and disinfection effects, but they are more irritating to the skin of the hands; some have mild skin care but have limited sterilization effects, and it is difficult to achieve a balance between the two, and it is even more difficult to achieve excellent skin care and sterilization effects

Method used

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  • Washing-free antibacterial hand sanitizer and preparation method thereof
  • Washing-free antibacterial hand sanitizer and preparation method thereof
  • Washing-free antibacterial hand sanitizer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The preparation of embodiment 1 hand sanitizer 1#

[0031] According to parts by weight, hand sanitizer 1# is prepared from the following raw materials: 90 parts of water, 40 parts of carbomer, 0.5 parts of p-chloro-m-dimethylphenol, 3 parts of magnesium aluminum silicate, 10 parts of organic alcohol, traditional Chinese medicine 8 parts of extract, 7 parts of chitosan nanoparticles and 2 parts of essence.

[0032] Wherein, the chitosan nanoparticle comprises carboxymethyl chitosan and quaternized chitosan, the weight ratio of carboxymethyl chitosan and quaternized chitosan is 5:2; quaternized chitosan is Prepared by reacting 2,3-epoxypropyltrimethylammonium chloride with chitosan.

[0033] The preparation method of chitosan nanoparticles is to add carboxymethyl chitosan and quaternized chitosan to water, stir and add sodium tripolyphosphate solution dropwise, then add ethylenediaminetetraacetic acid solution and ethanol solution, and ultrasonically After standing sti...

Embodiment 2

[0042] The preparation of embodiment 2 hand sanitizer 2#

[0043] According to parts by weight, hand sanitizer 2# is prepared from the following raw materials: 80 parts of water, 20 parts of carbomer, 0.1 part of p-chloro-m-dimethylphenol, 1 part of magnesium aluminum silicate, 5 parts of organic alcohol, traditional Chinese medicine 2 parts of extract, 1 part of chitosan nanoparticles and 1 part of essence.

[0044] Wherein, the chitosan nanoparticle comprises carboxymethyl chitosan and quaternized chitosan, the weight ratio of carboxymethyl chitosan and quaternized chitosan is 5:1; quaternized chitosan is Prepared by reacting 2,3-epoxypropyltrimethylammonium chloride with chitosan.

[0045] The preparation method of chitosan nanoparticles is to add carboxymethyl chitosan and quaternized chitosan to water, stir and add sodium tripolyphosphate solution dropwise, then add ethylenediaminetetraacetic acid solution and ethanol solution, and ultrasonically After standing still fo...

Embodiment 3

[0054] The preparation of embodiment 3 hand sanitizer 3#

[0055] According to parts by weight, hand sanitizer 3# is prepared from the following raw materials: 100 parts of water, 50 parts of carbomer, 1 part of p-chloro-m-xylphenol, 5 parts of magnesium aluminum silicate, 20 parts of organic alcohol, traditional Chinese medicine 10 parts of extract, 10 parts of chitosan nanoparticles and 5 parts of essence.

[0056] Wherein, the chitosan nanoparticle comprises carboxymethyl chitosan and quaternized chitosan, the weight ratio of carboxymethyl chitosan and quaternized chitosan is 5:3; quaternized chitosan is Prepared by reacting 2,3-epoxypropyltrimethylammonium chloride with chitosan.

[0057] The preparation method of chitosan nanoparticles is to add carboxymethyl chitosan and quaternized chitosan to water, stir and add sodium tripolyphosphate solution dropwise, then add ethylenediaminetetraacetic acid solution and ethanol solution, and ultrasonically After standing still fo...

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Abstract

The invention discloses a washing-free antibacterial hand sanitizer and a preparation method thereof, and belongs to the technical field of hand sanitizers, and the washing-free antibacterial hand sanitizer is prepared from the following raw materials in parts by weight: 80-100 parts of water, 20-50 parts of carbomer, 0.1-1 part of parachlorometaxylenol, 1-5 parts of magnesium aluminum silicate, 5-20 parts of organic alcohol, 2-10 parts of a traditional Chinese medicine extract, 1-10 parts of chitosan nanoparticles and 1-5 parts of essence. The hand sanitizer is added with natural traditional Chinese medicine components, is environment-friendly and harmless, is also added with chitosan nanoparticles, is mild and skin-friendly, has excellent sterilization and disinfection effects, and is mild and non-irritant to skin.

Description

technical field [0001] The application relates to a wash-free antibacterial hand sanitizer and a preparation method thereof, belonging to the technical field of hand sanitizers. Background technique [0002] Today, when the whole society advocates "saving water resources" and "protecting the environment", the hand sanitizer can save precious water resources and beautify the environment while ensuring health. The hand sanitizer does not need to use towels, water and soap. [0003] The advantages of disposable antibacterial hand sanitizer are: hand washing without water, easy to use and carry, long-lasting effect, the effect can last for 4-5 hours, up to 6 hours, and can effectively kill bacteria and viruses. Hand sanitizer can be used in hospitals, banks, supermarkets, government agencies, enterprises and institutions, theaters, troops, entertainment venues, large, middle and primary schools, kindergartens, families, hotels, restaurants, airports, docks, railway stations and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/26A61K8/34A61K8/73A61K8/81A61P31/02A61P31/04A61Q17/00A61Q19/10
CPCA61K8/9789A61K8/735A61K8/26A61K8/8147A61K8/347A61Q19/10A61Q17/005A61P31/02A61P31/04A61K2800/82A61K2800/5922A61K2800/413Y02A50/30
Inventor 唐地源孟庆文马俊国王艳孟会影赵玥
Owner SHANDONG ZHONGDA PHARMA
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