Tumor-bearing tissue model for US/CT-guided downlink tumor puncture or thermal ablation training and preparation method thereof

Abstract

The invention discloses a tumor-bearing tissue model for US / CT-guided downlink tumor puncture or thermal ablation training. The tumor-bearing tissue model comprises a normal tissue phantom and a tumor phantom embedded in the normal tissue phantom, the normal tissue phantom contains acrylamide gel, temperature-sensitive ink and sodium chloride; the tumor phantom contains acrylamide gel, temperature-sensitive ink, sodium chloride, a US contrast agent and a CT contrast agent; and the acrylamide gel is a gel formed by carrying out a polymerization cross-linking reaction on acrylamide and methylene bisacryl amide. According to the tumor-bearing tissue model, the position and size of a tumor can be accurately positioned and evaluated, and tumor puncture and thermal ablation training under the guidance of US / CT can be carried out; and the range of the coagulative necrosis area after thermal ablation can be simply and visually displayed in a color change mode, so that the tumor thermal ablation effect can be accurately evaluated. The invention also discloses a preparation method of the tumor-bearing tissue model, which is simple to operate, low in cost, efficient in reaction, easy in process control, green and environment-friendly.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to the field of interventional therapy, and relates to a tumor-bearing tissue model for US / CT-guided downward tumor puncture or thermal ablation training and a preparation method thereof. Background technique [0002] Imaging-guided thermal ablation therapy, as an interventional therapy, is widely used in the clinical treatment of tumors in various parts of the human body, such as liver, breast, and thyroid. The basic operation is to insert the ablation needle into the tumor under the precise guidance of imaging (such as ultrasound, CT, etc.) and cause a large amount of heat to be generated locally in the tumor tissue. The main principle is that when the temperature reaches about 60°C, the tumor cells will immediately undergo coagulation necrosis, so as to achieve the purpose of killing tumor cells. [0003] In recent years, imaging-guided thermal ablation technology has been developed rapi...

AI Technical Summary

Problems solved by technology

Unfortunately, none of them give an accurate method for assessing the extent of tumor ablation

Images