Application of cistanche deserticola polysaccharides in preparation of cosmetics with moisture absorption, moisture preservation or soothing effects

A technology of Cistanche deserticola polysaccharide and cosmetics, which is applied in the directions of cosmetics, cosmetic preparations, cosmetic preparations, etc., can solve the problems that the moisture absorption and moisturizing properties have not yet been seen.

Pending Publication Date: 2021-12-24
GUANGZHOU YUMING BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Nowadays, there have been a lot of studies on the pharmacological effects of Cistanche deserticola polysaccharides such as immune regulation, anti-fatigue, anti-oxidation, anti-aging, improving learning ability, anti-liver damage, anti-virus, anti-tumor, etc., but there is no research on its moisture absorption and moisturizing properties. see

Method used

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  • Application of cistanche deserticola polysaccharides in preparation of cosmetics with moisture absorption, moisture preservation or soothing effects
  • Application of cistanche deserticola polysaccharides in preparation of cosmetics with moisture absorption, moisture preservation or soothing effects
  • Application of cistanche deserticola polysaccharides in preparation of cosmetics with moisture absorption, moisture preservation or soothing effects

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0028] The preparation method of Cistanche deserticola polysaccharide of the present invention is as follows:

[0029] The present invention extracts Cistanche cistanche polysaccharides through a composite enzyme combined with ultrasonic extraction method. The specific operation method is: weigh an appropriate amount of deesterified Cistanche cistanche powder and cellulase (2wt%, the weight percentage of enzyme and acid water), papain (2wt%, enzyme weight percentage with acid water), pectinase (0.45wt%, weight percentage of enzyme and acid water), according to the ratio of material to liquid 1:10, add acid water for enzymolysis extraction, adjust the temperature to 54-54.5 ° C, put in a water bath Enzymolysis in the pot for 1.5-2.5h, then ultrasonic extraction 3 times, each ultrasonic extraction 25-35min, the first ultrasonic extraction liquid is enzymatic hydrolysis liquid, acid water is added to the last two ultrasonic extractions, the ratio of solid to liquid is 1 :10, filt...

Embodiment 1

[0035] Hygroscopic and moisturizing effect of embodiment 1 cistanche polysaccharide

[0036] (1) Test materials and instruments

[0037] 1.1 Experimental materials

[0038] Desert cistanche (deesterified).

[0039] 1.2 Enzymes and reagents for testing

[0040] Table 1 Enzymes and reagents used in experiments

[0041]

[0042] 1.3 Experimental Instruments

[0043] Table 2 The experimental equipment used to extract polysaccharides from Cistanche deserticola

[0044]

[0045] (2) Experimental method

[0046] 2.1 Preparation of Cistanche polysaccharide

[0047] Weigh 3200g deesterified Cistanche deserticola powder, 64g cellulase, 64g papain, 14.4g pectinase, add 32000g acid water for enzymatic extraction, adjust the temperature to 54.1°C, put it in a water bath for 2 hours, and then ultrasonically extract 3 times, ultrasonic extraction for 30 minutes each time, the first ultrasonic extraction was an enzymatic hydrolysis solution, and 32000g of acid water was added each ...

Embodiment 2

[0096]Example 2 Cistanche deserticola polysaccharide composition soothing effect (zebrafish acute irritation test result)

[0097] On the basis of the previous evaluation of moisturizing properties, the inventor of the present application continued to refer to the "Cosmetic Safety Experiment (Zebrafish) Experimental Method" standard issued by the Huangpu Cosmetics Industry Association of Guangzhou Development Zone, and tested the soothing effect of related traditional Chinese medicine polysaccharides through mild irritation. Tests are rated.

[0098] (1) Experimental method: Determination of mild irritation of cosmetics by zebrafish embryo method

[0099] 1 This standard specifies the method principle and operation of the zebrafish embryo experiment for evaluating the mild irritation of cosmetics. This standard is applicable to mild irritation evaluation of cosmetics (cream, lotion, gel, essence, etc.) and cosmetic raw materials.

[0100] 2 Cosmetics Safety Technical Specifi...

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Abstract

The invention provides application of cistanche deserticola polysaccharides in preparation of cosmetics with moisture absorption, moisture preservation or soothing effects. A preparation method of the cistanche deserticola polysaccharides comprises the following steps of extracting cistanche deserticola by a compound enzyme combined ultrasonic extraction method, precipitating an extracting solution by using ethanol until the ethanol concentration is 80% to obtain precipitates which are crude polysaccharides, volatilizing the ethanol, adding water for dissolving, and then adding ethanol for purifying to obtain ethanol precipitated cistanche deserticola polysaccharides, wherein a compound enzyme is cellulase, papain and pectinase. According to the invention, the three kinds of cistanche deserticola polysaccharides all have certain moisture absorption and moisture retention effects, the 50% and 80% ethanol precipitated cistanche polysaccharides have soothing effects, and the cistanche deserticola polysaccharides have certain research value in the field of cosmetics in combination with the physiological activities of aging resistance, oxidation resistance and the like.

Description

technical field [0001] The invention relates to the application of Cistanche deserticola polysaccharide in preparing cosmetics with hygroscopic, moisturizing or soothing effects. Background technique [0002] The scientific name of Cistanche deserticola is Cistanche deserticola Ma, which is a parasitic plant of the genus Cistanche. Its medicinal part is its dry and scaly fleshy stem. It was first recorded in "Shen Nong's Materia Medica". , is a precious Chinese herbal medicine that is commonly used in Chinese medicine clinics and has the effect of strengthening yang. It has a long history of use, and it is recorded in ancient my country's "Bie Yi Zhi Lu" (late Han Dynasty), "Ben Cao Jing Ji Zhu" (Northern and Southern Dynasties), "Qian Jin Yi Fang" (Tang Dynasty), "Compendium of Materia Medica" (Ming Dynasty), etc. It has the reputation of "desert ginseng", also known as goblin, golden bamboo shoots, big yun and so on. There are five main types of Cistanche distributed in m...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61Q19/00C08B37/00
CPCA61K8/73A61Q19/00C08B37/0003A61K2800/82A61K2800/805A61K2800/10
Inventor 刘小花王少华刘珈铭王昊戴伟昊
Owner GUANGZHOU YUMING BIOLOGICAL TECH CO LTD
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