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Traditional Chinese medicine composition for treating radioactive injury and preparation method thereof

A composition and technology of traditional Chinese medicine components, applied in the field of traditional Chinese medicine composition and its preparation, Chinese medicine composition for treating radiation damage and its preparation, can solve problems such as unsatisfactory curative effect, strong drug dependence, and large side effects

Active Publication Date: 2021-12-21
THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing treatment methods have long treatment cycle, strong drug dependence, large side effects, and unsatisfactory curative effect. Therefore, the development of drugs that can avoid or reduce radiation damage has become the focus of research.

Method used

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  • Traditional Chinese medicine composition for treating radioactive injury and preparation method thereof
  • Traditional Chinese medicine composition for treating radioactive injury and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] The preparation of embodiment 1 oral liquid

[0076] Raw rehmannia 40g Ophiopogon japonicus 35g Scrophulariaceae 20g

[0077] Codonopsis 60g Scutellaria baicalensis 60g Fritillaria 60g

[0078] Shegan 20g Pinellia 20g White Peony 20g

[0079] Danshen 45g, Moutan bark 60g, Magnolia officinalis 45g

[0080] Poria cocos 20g Mint 10g Coptis 10g

[0081] A. Weigh raw rehmannia glutinosa, Ophiopogon japonicus, Scrophulariaceae, Codonopsis baicalensis, Scutellaria baicalensis, Fritillaria japonicus, Shegan, Pinellia, Radix Paeoniae Alba, Salvia miltiorrhiza, Cortex Moutan, Magnolia officinalis, Poria cocos, Mint, and Coptis chinensis. , Codonopsis, Fritillaria, Salvia, and Poria cocos are cleaned and cut into thick slices; Pinellia pinellia is processed into broiled pinellia after net selection, and Radix japonicus is squished after net selection, dried, and set aside;

[0082] B. Take the above 15 medicinal herb pieces, add 9 times the amount of water to decoct twice, th...

Embodiment 2

[0084] The preparation of embodiment 2 granules

[0085] Raw rehmannia 65g Ophiopogon japonicus 54g Scrophulariaceae 45g

[0086] Codonopsis 35g Scutellaria baicalensis 35g Fritillaria 35g

[0087] Shegan 45g Pinellia 45g Paeoniae Alba 45g

[0088] Danshen 25g, Moutan bark 35g, Magnolia officinalis 26g

[0089] Poria cocos 45g Mint 25g Coptis 25g

[0090] A. Weigh raw rehmannia glutinosa, Ophiopogon japonicus, Scrophulariaceae, Codonopsis baicalensis, Scutellaria baicalensis, Fritillaria japonicus, Shegan, Pinellia, Radix Paeoniae Alba, Salvia miltiorrhiza, Cortex Moutan, Magnolia officinalis, Poria cocos, Mint, and Coptis chinensis. , Codonopsis, Fritillaria, Salvia, and Poria cocos are cleaned and cut into thick slices; Pinellia pinellia is processed into broiled pinellia after net selection, and Radix japonicus is squished after net selection, dried, and set aside;

[0091] B. Take the above 15 medicinal herb pieces, add 2 times the amount of water to decoct twice, the...

Embodiment 3

[0093] The preparation of embodiment 3 oral liquid

[0094] Raw rehmannia 60g Ophiopogon japonicus 48g Scrophulariaceae 40g

[0095] Codonopsis 40g Scutellaria baicalensis 40g Fritillaria 40g

[0096] Shegan 40g Pinellia 40g Paeoniae Alba 40g

[0097] Danshen 30g, Moutan bark 40g, Magnolia officinalis 32g

[0098] Poria cocos 40g Mint 20g Coptis 20g

[0099] A. Weigh raw rehmannia glutinosa, Ophiopogon japonicus, Scrophulariaceae, Codonopsis baicalensis, Scutellaria baicalensis, Fritillaria japonicus, Shegan, Pinellia, Radix Paeoniae Alba, Salvia miltiorrhiza, Cortex Moutan, Magnolia officinalis, Poria cocos, Mint, and Coptis chinensis. , Codonopsis, Fritillaria, Salvia, and Poria cocos are cleaned and cut into thick slices; Pinellia pinellia is processed into broiled pinellia after net selection, and Radix japonicus is squished after net selection, dried, and set aside;

[0100] B. Take the above 15 medicinal herb pieces, add 8 times the amount of water to decoct twice, ...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating radioactive injury and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following 15 raw medicinal materials: radix rehmanniae recen, radix ophiopogonis, radix scrophulariae, codonopsis pilosula, scutellaria baicalensis, thunberg fritillary bulb, blackberry lily, pinellia ternate, white paeony root, salvia miltiorrhiza, moutan bark, mangnolia officinalis, poria cocos, mint and coptis chinensis. The composition in the invention is mild in medicine property, precise and appropriate in compatibility and synergistic in effect, has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, nourishing lung and kidney and replenishing qi to invigorate the spleen, and is suitable for diseases such as mouth dryness, pharyngalgia, toothache, dry cough and chronic rhinitis caused by acute and chronic radioactive injuries and radiotherapy. Pharmacodynamic tests show that the composition disclosed by the invention has an exact treatment effect on radiation-induced lung injury and radiation-induced intestine injury.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating radiation damage and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Radiation therapy (radiation therapy, RT) is a local treatment method that uses radiation to treat tumors. About 70% of cancer patients need radiation therapy during the treatment of cancer, and about 40% of cancers can be cured by radiotherapy. Therefore, Radiation therapy has become one of the main means of treating various malignant tumors. Although radiation therapy can kill tumor cells, it also inevitably causes damage to normal tissues, destroys the immune function of the body, and produces a series of radiation injuries. The clinical manifestations of patients with radiation injury are characterized by damage to multiple systems...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P17/16A61P1/02A61P11/04A61P11/14A61P11/02
CPCA61K36/804A61K36/8968A61K36/808A61K36/344A61K36/539A61K36/8966A61K36/88A61K36/8888A61K36/71A61K36/65A61K36/537A61K36/575A61K36/076A61K36/534A61K36/718A61P17/16A61P1/02A61P11/04A61P11/14A61P11/02A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 曲政海于壮张业玲关永霞李蕾
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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