Preparation method and preparation equipment of biomimetic mineralized collagen scaffolds

Abstract

The invention belongs to the technical field of mineralized collagen scaffolds, and discloses preparation equipment of biomimetic mineralized collagen scaffolds. The preparation equipment comprises a pressing chamber, a pressing plate is movably connected to an inner cavity of the pressing chamber, an annular rack is fixedly mounted on the top surface of the pressing plate, a pressing motor is fixedly mounted on the top surface of the pressing chamber, the output end of the pressing motor is fixedly sleeved with a first gear, and the inner cavity of the pressing chamber is movably connected with a grinding plate. According to the preparation equipment, a third gear is driven by a grinding motor to rotate, the grinding plate is driven to rotate when the third gear rotates, the pressing plate can be driven to rotate in the opposite direction when the grinding plate rotates through meshing of a driving gear, a planetary gear and a gear ring, during rotation, after compression molding, through downward movement of the pressing plate and the grinding plate, a biomimetic collagen block can be directly ground, the biomimetic collagen block does not need to be taken out through a special tool, operation is easy, and the labor difficulty of operators is lowered.

Description

technical field [0001] The invention belongs to the technical field of mineralized collagen scaffolds, in particular to a method for preparing a bionic mineralized collagen scaffold and a preparation device thereof. Background technique [0002] Vertebrate hard tissues are formed through the mineralization process of living systems. Mineralized collagen is the basic structural unit of these biological materials. Mineralized collagen is an organic-inorganic composite material formed by collagen molecules and nano-calcium phosphate minerals. The unique nano-ordered multi-level structure endows biological hard woven materials with excellent mechanical properties. The biomimetic mineralized collagen scaffold is a product used to replace mineralized collagen. It is widely used, so it needs to use a special preparation device for mass production. [0003] When the existing preparation device is in use, stirring, compression molding and grinding are required during the preparation ...

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Problems solved by technology

[0003] When the existing preparation device is in use, stirring, compression molding and grinding are required during the preparation process, and the biomimetic mineralized collagen powder is pressed into a biomimetic mineralized collagen block through the compression mold, but in actual use, operators are required to Use a pressure device to apply pressure. After pressing, the bionic mineralized collagen block needs to be taken out of the pressure device. When taking it out, a special tool is required to take out the bionic mineralized collagen block. The operation is complicated , increasing the labor difficulty of the operator

[0004] In the current preparation device, after the bionic mineralized collagen block is taken out, the bionic mineralized collagen block needs to be placed in a grinding device for grinding into a bionic mineralized collagen scaffold. When in use, the operator needs to press the bionic mineralized collagen block from Take it out, and then place it in the grinding equipment. Due to the high pressure exerted by the compression molding device, it is laborious to take out the bionic collagen block, which reduces the work efficiency of the operator.

[0005] When the existing preparation device is in use, the biomimetic collagen powder needs to be pressed. When the pressure on the biomimetic collagen powder reaches a certain level, the pressure needs to be maintained for a certain period of time. Most of the existing pressure-applying components need to Continuously supplying power to the parts applying pressure to achieve the effect of maintaining pressure requires a large amount of energy consumption and increases the cost of the device

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