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Active micro-fluidic chip based on magnetic blending technology and use method thereof

A microfluidic chip and technology, applied in chemical instruments and methods, mixers, laboratory containers, etc., can solve problems such as unsatisfactory mixing effect, inaccurate test results, and insufficient immune response, etc., to achieve Convenient transportation, ensuring accuracy, and strengthening the effect of preventing backflow

Pending Publication Date: 2021-09-21
NANJING LANSION BIOTECH CO LTD
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Problems solved by technology

[0003] In the active microfluidic chips that have been put into use at present, both the labeled antibody and the coated antibody are set in the quantitative-reaction chamber. The mixing effect of the three is not ideal, resulting in insufficient immune response and low efficiency, resulting in inaccurate test results

Method used

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  • Active micro-fluidic chip based on magnetic blending technology and use method thereof
  • Active micro-fluidic chip based on magnetic blending technology and use method thereof
  • Active micro-fluidic chip based on magnetic blending technology and use method thereof

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Embodiment Construction

[0070] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some of the embodiments of the present invention, not all of them. The following description of at least one exemplary embodiment is merely illustrative in nature and in no way taken as limiting the invention, its application or uses. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention. The relative arrangements, expressions and numerical values ​​of components and steps set forth in these embodiments do not limit the scope of the present invention unless specifically stated otherwise. At the same time, it should be understood that, for the convenience of description, th...

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Abstract

The invention discloses an active micro-fluidic chip based on a magnetic mixing technology and a use method thereof. The micro-fluidic chip comprises a chip body, and the chip body is provided with a sample injection cavity, a quantification-reaction cavity and a waste liquid cavity; a labeled antibody is attached in the sample injection cavity, and a plurality of magnetic parts are preset in the sample injection cavity; and the external liquid path interface is correspondingly communicated with the quantitative-reaction cavity through the external flow path micro-flow channel, and a coating antibody is attached to the interior of the quantitative-reaction cavity. Therefore, the uniform mixing reaction effect of the sample and the labeled antibody in the sample injection cavity can be effectively ensured, so that the sufficient immune reaction of the sample and the coated antibody in the quantitative reaction cavity is effectively ensured, and the high accuracy of the detection result of the micro-fluidic chip is ensured.

Description

technical field [0001] The invention relates to an active microfluidic chip, in particular to an active microfluidic chip based on magnetic mixing technology and a use method thereof. Background technique [0002] Microfluidic chip technology is characterized by a micropipeline network, using micromachining technology to etch a micropipeline network and other functional units on a chip of a few square centimeters in size, thereby preparing a microfluidic chip that includes injection, reaction, separation, and detection An integrated fast, efficient, and low-consumption micro-analysis device. The microfluidic chip has the characteristics of less reagent consumption, short reaction time and high degree of automation in the detection platform. [0003] In the active microfluidic chip that has been put into use at present, both the labeled antibody and the coated antibody are set in the quantitative-reaction chamber. The mixing effect of the three is not ideal, resulting in in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00B01F13/08G01N33/543
CPCB01L3/5027G01N33/54326
Inventor 许行尚杰弗瑞·陈王龙刘祥
Owner NANJING LANSION BIOTECH CO LTD
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