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Preparation method and application of allergy-relieving and repairing compound

A complex and soothing technology, which is applied in the field of soothing repair complex and preparation, can solve the problems of incomplete effect and poor binding effect of the complex solution.

Inactive Publication Date: 2021-09-07
悠宜生物科技(江苏)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the problem that the compound liquid in the prior art has poor binding effect and the effect cannot be fully exerted, a preparation method of a soothing and repairing compound is proposed, which is characterized in that: golden chamomile extract, gentian extract , grape skin extract, olive leaf extract, centella asiatica flower / leaf / stem extract, purslane flower / leaf / stem extract, citrus fruit extract and dextran heated to 70-80°C and stirred to dissolve; The soothing and repairing compound is compounded according to the following weight components: including 15-25% golden chamomile extract, 10-15% gentian extract, 5-10% grape skin extract, 5-10% Olive leaf extract, 5-10% centella asiatica flower / leaf / stem extract, 5-8% purslane flower / leaf / stem extract, 3-5% citrus fruit extract and 1-5% % Dextran

Method used

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  • Preparation method and application of allergy-relieving and repairing compound
  • Preparation method and application of allergy-relieving and repairing compound
  • Preparation method and application of allergy-relieving and repairing compound

Examples

Experimental program
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Effect test

Embodiment 1

[0034] 1. The temperature used for the extraction of golden chamomile is 65°C, the weight ratio of solid to liquid is 1:22, and the ultrasonic-assisted extraction time is 75min. After that, it is heated and boiled, concentrated to a density of 1.10g / mL (60°C), and filtered through double-layer gauze. The filtrate is added with butanediol to configure a solution with a ratio of liquid to butanediol of 1:1.

[0035] 2. Gentiana and 50% ethanol are used as solvent extraction for 3 times, the weight ratio of material to liquid for the first time is 1:10, the weight ratio of material to liquid for the second time is 1:8, and the weight ratio of material to liquid for the third time is 1:8. The extraction temperature was 70° C., the extraction time was 4 hours, filtered, the three filtrates were combined, concentrated at 80° C. to remove ethanol, and dried in vacuum to obtain the gentian extract.

[0036] 3. Grape skin extraction uses ethyl acetate as solvent, the weight ratio of so...

Embodiment 2

[0043] 1. The temperature used for the extraction of golden chamomile is 50°C, the weight ratio of solid to liquid is 1:15, and the ultrasonic-assisted extraction time is 70 minutes, then heated and boiled, concentrated to a density of 1.08g / mL (60°C), and filtered through double-layer gauze The filtrate is added with butanediol to configure a solution with a ratio of liquid to butanediol of 1:1.

[0044] 2. Gentiana and 70% ethanol are used as solvent extraction for 3 times, the weight ratio of material to liquid for the first time is 1:8, the weight ratio of material to liquid for the second time is 1:5, and the weight ratio of material to liquid for the third time is 1:5. The extraction temperature was 80° C., the extraction time was 5 hours, filtered, the three filtrates were combined, the ethanol was concentrated at 80° C., and vacuum-dried to obtain the gentian extract.

[0045] 3. Grape skin extraction uses ethyl acetate as a solvent, the weight ratio of solid to liquid...

Embodiment 3

[0052] 1. The temperature used for the extraction of golden chamomile is 65°C, the weight ratio of solid to liquid is 1:25, and the ultrasonic-assisted extraction time is 90 minutes, then heated and boiled, concentrated to a density of 1.10g / mL (60°C), and filtered through double-layer gauze The filtrate is added with butanediol to configure a solution with a ratio of liquid to butanediol of 1:1.

[0053] 2. Gentiana and 75% ethanol are used as solvent extraction for 3 times, the weight ratio of material to liquid for the first time is 1:10, the weight ratio of material to liquid for the second time is 1:8, and the weight ratio of material to liquid for the third time is 1:8. The extraction temperature was 80° C., the extraction time was 4 hours, filtered, the three filtrates were combined, the ethanol was concentrated at 80° C., and vacuum-dried to obtain the gentian extract.

[0054] 3. Grape skin extraction uses ethyl acetate as a solvent, the weight ratio of solid to liqui...

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Abstract

The invention provides a preparation method and application of an allergy-relieving and repairing compound, and belongs to the technical field of cosmetics. The preparation method comprises the following steps of: heating a chrysanthellum indicum extract, a radix gentianae extract, a grape skin extract, an olive leaf extract, a centella asiatica flower / leaf / stem extract, a purslane flower / leaf / stem extract, a trifoliate orange fruit extract and glucan to 70-80 DEG C, and stirring for dissolving. The allergy-relieving and repairing compound is compounded from the following components in percentage by weight: 15-25% of the chrysanthellum indicum extract, 10-15% of the radix gentianae extract, 5-10% of the grape skin extract, 5-10% of the olive leaf extract, 5-10% of the centella asiatica flower / leaf / stem extract, 5-8% of the purslane flower / leaf / stem extract, 3-5% of the trifoliate orange fruit extract and 1-5% of the glucan. The allergy-relieving and repairing compound can effectively solve the problems that a single extract is poor in effect and the effect cannot be completely exerted, and has a better allergy-relieving and repairing effect on skin.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a soothing and repairing compound as well as its preparation method and application. Background technique [0002] In recent years, with changes in dietary structure, air pollution, and increased pressure in life and work, the number of allergic patients has increased dramatically. According to the 2017 and 2018 statistics of the five dermatological diagnosis institutions identified by the Ministry of Health of my country, contact dermatitis is the most common of the six major cosmetic dermatological diseases, and the two-year incidence rate accounts for 82.6% and 93.3%. There are a lot of chemical additives in most cosmetics on the market, which can easily cause skin sensitivity and even inflammation. Sensitive skin is very prone to allergies when using ordinary cosmetics. Cosmetics with soothing, repairing and anti-irritant effects are gaining more and more attention, and su...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/73A61K36/87A61Q19/00A61Q17/00A61P29/00A61K31/716
CPCA61K8/9789A61K8/73A61Q19/005A61Q19/00A61Q17/005A61P29/00A61K36/28A61K36/515A61K36/87A61K36/63A61K36/23A61K36/185A61K36/75A61K31/716A61K2800/5922A61K2800/805A61K2300/00
Inventor 陈秀玉王绍梅秦涛郭星星詹柱刘晓磊丁冲冲郑海兵何沪宝
Owner 悠宜生物科技(江苏)有限公司
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