Anti-wrinkle skin-care cosmetic composition containing polypeptide and preparation method of anti-wrinkle skin-care cosmetic composition
A technology of cosmetic composition and skin care cosmetics, which is applied in the direction of cosmetic preparations, cosmetics, medical preparations containing active ingredients, etc., which can solve the problems of non-permanent, insignificant anti-wrinkle effect, and not very prominent anti-wrinkle effect, so as to promote Metabolism, enhanced skin immunity, anti-wrinkle effect outstanding effect
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Embodiment 1
[0052] The preparation method of ajirelin is as follows:
[0053]S1. Weigh 100g of Rink Amide-AM Resin resin with a substitution degree of 0.70mmol / g into the reaction column, add an appropriate amount of DCM to swell for 15min, drain it, wash it with DMF for 3 times, then drain it, and add an appropriate amount of decapping solution to react for 5min Finally, drain the capping liquid, wash once with an appropriate amount of DMF, then add an appropriate amount of capping liquid to react for 10 minutes, drain the capping liquid, wash 6 times with DMF, and dry it. Wherein, the capping liquid is composed of DBLK and DMF according to the volume ratio of 1:4 configuration;
[0054] S2. Weigh 148.02g of Fmoc-Arg(pbf)-Arg(pbf)-OH and 44.95g of TBTU, completely dissolve in an appropriate amount of DMF, slowly add 46.28ml of DIEA under ice-bath conditions, and stir slowly, and the uniformly stirred Fmoc- The mixed solution of Arg(pbf)-Arg(pbf)-OH / TBTU / DIEA was slowly added to the reac...
Embodiment 2
[0060] The preparation method of cucumber extract is as follows:
[0061] S1. Weighing raw materials in percentage by weight: cucumber extract 8%, glycerin 6%, tocopherol 3%, myristyl alcohol 2%, pentylene glycol 4%, deionized water 77%;
[0062] S2. Add glycerin, myristyl alcohol, and pentylene glycol to water, heat to 75° C. to melt, and stir evenly while heating;
[0063] S3. Cool the dissolved glycerin, myristyl alcohol, and pentylene glycol mixture to 42°C, slowly add cucumber extract and tocopherol during stirring, stir and mix evenly and slowly cool to 28°C, then seal to obtain cucumber extract things.
Embodiment 3
[0065] The preparation method of honeysuckle extract is as follows:
[0066] S1. Weigh the raw materials in percentage by weight: 6% of honeysuckle extract, 7% of glycerin, 2% of butylated hydroxytoluene, 1% of myristyl alcohol, 2% of pentylene glycol, and 82% of deionized water;
[0067] S2. Add glycerin, myristyl alcohol, and pentylene glycol to water, heat to 75° C. to melt, and stir evenly while heating;
[0068] S3. Cool the dissolved glycerin, myristyl alcohol, and pentylene glycol mixture to 40°C, slowly add honeysuckle extract and butylated hydroxytoluene during the stirring process, stir and mix evenly, slowly cool to 28°C, and then seal to obtain honeysuckle Extract.
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