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Composition, extraction method and application of composition in anti-inflammatory field

An extraction method and composition technology, applied in the field of anti-inflammation, the field of composition, can solve the problems of gastrointestinal tract injury stimulation, insufficient efficacy, easy to produce drug resistance, etc., to achieve a wide range of action and efficacy Long-lasting, immune-boosting effect

Inactive Publication Date: 2021-08-10
GUANGDONG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In view of this, the present invention provides a composition, an extraction method and its application in the field of anti-inflammation, which are used to solve the problems in the prior art that artificially synthesized anti-inflammatory drugs have a narrow application range, insufficient durability, and are harmful to the stomach. The intestinal tract has noxious stimulation and technical defects that are prone to drug resistance

Method used

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  • Composition, extraction method and application of composition in anti-inflammatory field
  • Composition, extraction method and application of composition in anti-inflammatory field
  • Composition, extraction method and application of composition in anti-inflammatory field

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Garlic, purslane and purslane were washed and air-dried naturally, 100 g of garlic, 150 g of purslane and 150 g of purslane were mixed, dried at 70°C for 40 minutes, and then pulverized through a 30-mesh sieve to obtain the first product 1.

[0034] After 228 g of the first product 1 was degreased, it was soaked in 2.28 L of 75% ethanol to obtain the second product 1.

[0035] The second product 1 was ultrasonically treated at 45°C for 40 min, the filtrate was collected by suction filtration, and the filtrate was concentrated under reduced pressure at 30°C to obtain the third product 1.

[0036] The third product 1 was freeze-dried at -50°C for 11 h to obtain product 1.

Embodiment 2

[0038] Garlic, purslane and purslane were washed and air-dried naturally. 100 g of garlic, 150 g of purslane and 150 g of purslane were mixed, dried at 50°C for 40 min, and then pulverized through a 20-mesh sieve to obtain the first product 2.

[0039] After 254g of the first product 2 was degreased, it was soaked in 2.54L of 75% ethanol to obtain the second product 2.

[0040] The second product 2 was ultrasonically treated at 30°C for 40 min, the filtrate was collected by suction filtration, and the filtrate was concentrated under reduced pressure at 45°C to obtain the third product 2.

[0041] The third product 2 was freeze-dried at -50°C for 10 h to obtain product 2.

Embodiment 3

[0043] Garlic, purslane and purslane were washed and air-dried naturally, 100 g of garlic, 150 g of purslane and 150 g of purslane were mixed, dried at 40°C for 40 min, and then pulverized through a 40-mesh sieve to obtain the first product 3.

[0044] After 297 kg of the first product 3 was degreased, it was soaked in 2.97 L of 75% ethanol to obtain the second product 3.

[0045] The second product 3 was ultrasonically treated at 60°C for 40 min, the filtrate was collected by suction filtration, and the filtrate was concentrated under reduced pressure at 50°C to obtain the third product 3.

[0046] The third product 3 was freeze-dried at -50°C for 10 h to obtain product 3.

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Abstract

The invention belongs to the technical field of natural medicines, and particularly relates to a composition, an extraction method and application of the composition in the anti-inflammatory field. The composition is prepared from the following raw materials: garlic, herba portulacae and acanthopanax trifoliatus. The invention also provides the extraction method of the composition. The invention also provides the application of the composition or a product obtained by the extraction method in the anti-inflammatory field. In the technical scheme provided by the invention, the natural extracts have the advantages of strong antibacterial property, lasting effect and wide action range, and meanwhile, the three extracts have a certain synergistic effect and also have the comprehensive gain effects of clearing away heat and toxic materials, enhancing immunity and resisting fatigue. According to the composition, the extraction method and the application of the composition in the anti-inflammatory field, the technical defects that in the prior art, artificially synthesized anti-inflammatory drugs are narrow in application range, not long enough in efficacy, harmful and irritant to gastrointestinal tracts and prone to drug resistance are overcome.

Description

technical field [0001] The invention belongs to the technical field of natural medicines, and in particular relates to a composition, an extraction method and its application in the field of anti-inflammatory. Background technique [0002] Purslane is a plant of the purslane family, widely distributed in temperate and tropical regions. It has a long history of medicinal use, and herbal medicine has been recorded. Purslane contains alkaloids, flavonoids, coumarins, terpenes, proteins, fats, minerals and other ingredients. It has the effects of clearing heat, detoxification, cooling blood, and reducing swelling. It can be used to treat dysentery, diarrhea and other symptoms. Existing research shows that purslane extract has antioxidant, antibacterial, anti-fatigue and other effects. Purslane extract has a high degree of inhibitory effect on most gram-negative bacteria, and also has different degrees of inhibition on some gram-positive bacteria. [0003] Garlic is a semi-annu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61P29/00A61P39/02A61P39/00A61P37/04
CPCA61K36/185A61K36/254A61K36/8962A61K2236/15A61K2236/333A61K2236/51A61K2236/53A61P29/00A61P37/04A61P39/00A61P39/02A61K2300/00
Inventor 赵肃清李双祁梁雨昕吴盼盼张炳杰
Owner GUANGDONG UNIV OF TECH
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