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Double-layer milk cover essence matrix and preparation method thereof

A technology of essence and milk cap, which is applied in the direction of pharmaceutical formulations, cosmetic preparations, cosmetic preparations, etc. It can solve the problem of reducing the viscosity of dispersion solvents, detrimental to the stability of the double-layer milk cap essence matrix, and the inability to add polymers to thicken agent and other issues

Active Publication Date: 2021-07-30
广州市奥源贸易有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the actual use process, in order to make the layering faster, the viscosity of the dispersion solvent must be reduced, that is to say, basically no polymer thickener can be added, which is very unfavorable for the formulation of double-layer milk cap essence base. stability

Method used

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  • Double-layer milk cover essence matrix and preparation method thereof
  • Double-layer milk cover essence matrix and preparation method thereof
  • Double-layer milk cover essence matrix and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] This example examines the effect on the stability of the matrix when the ratio of sucrose laurate and laureth-23 added to the double-layer milk cap essence matrix is ​​0.5%:0.5%. The components and percentage contents of the double-layer milk cap essence matrix forming the present embodiment are shown in the following table:

[0046]

[0047]

[0048] The preparation method of the above double-layer milk cap essence matrix includes the following steps: mix Ryto Sugar Ester L-1695 with the polyol in the formula evenly at a temperature of 60°C, and the stirring speed is 200-300rpm, and the outside is completely wetted Then heat to 75-85°C until slightly viscous and transparent (it is also recommended to infiltrate in advance to help dissolve evenly); dissolve ALKONATL230 and other water-soluble ingredients in phase A in the remaining water phase; heat to 75-85°C; Under the temperature, add phase B into the water phase for emulsification, homogenize for 5-10 minutes, a...

Embodiment 2

[0050] This example examines the effect on the stability of the matrix when the ratio of sucrose laurate and laureth-23 added to the double-layer milk cap essence matrix is ​​0.1%:0.9%. The components and percentage contents of the double-layer milk cap essence matrix forming the present embodiment are shown in the following table:

[0051]

[0052] The preparation method of the above-mentioned double-layer milk cap essence liquid matrix is ​​consistent with the preparation method of Example 1.

Embodiment 3

[0054] This example examines the effect on the stability of the matrix when the ratio of sucrose laurate and laureth-23 added to the double-layer milk cap essence matrix is ​​0.2%:0.8%. The components and percentage contents of the double-layer milk cap essence matrix forming the present embodiment are shown in the following table:

[0055]

[0056] The preparation method of the above-mentioned double-layer milk cap essence liquid matrix is ​​consistent with the preparation method of Example 1.

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Abstract

The invention relates to a double-layer milk cover essence matrix which comprises a nonionic emulsifier, a polyhydric alcohol humectant, low-density skin moistening grease, an oil-soluble active matter and the like, wherein the nonionic emulsifier is obtained by compounding sucrose laurate and lauryl alcohol polyethers. The preparation method is characterized by adding a specific variety of polyhydric alcohol in a specific proportion for regulation, selecting a specific variety of nonionic emulsifier in a specific proportion, and adding low-density skin moistening grease and other common auxiliary components for cosmetics, so that the double-layer milk cover essence matrix with excellent skin feeling, good mildness and high stability is prepared. When the essence matrix is applied to medicines and / or cosmetics, the high stability of the essence matrix can effectively overcome the problem that the stability is interfered with by high temperature difference and the like in the use process, the storage process and the transportation process of cosmetics / medicines in actual life, and the good mildness of the essence matrix further widens the application range of the double-layer milk cover essence matrix.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a double-layer milk cap essence base and a preparation method thereof. Background technique [0002] Emulsion systems are thermodynamically unstable systems that will separate over time if formulation stability is not modulated. The main unstable phenomenon or metastable stage of the emulsion is mainly divided into four stages according to the order of occurrence time: ① stratification; ② flocculation; ③ merger; ④ Ostwald ripening or even demulsification and phase inversion. The double-layer milk cap essence base is actually the first stage of the ordinary emulsion-layered state. It has a unique and novel appearance. As a delivery system, compared with the traditional single-layer emulsion, the double-layer emulsion is more stable in structure. It has more advantages in resisting environmental pressure (such as pH, temperature and ionic strength, etc.), can provide better protection for...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/86A61K8/60A61K8/34A61K8/31A61K8/58A61K8/03A61Q19/00A61K47/26A61K47/10
CPCA61K8/86A61K8/604A61K8/345A61K8/31A61K8/585A61K8/03A61Q19/00A61Q19/005A61K47/26A61K47/10A61K2800/30A61K2800/592Y02A50/30
Inventor 周晶胡琴霞黎碧霞罗曼君
Owner 广州市奥源贸易有限公司
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