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Feed additive capable of replacing antibiotics and preparation method thereof

A feed additive, a technology to replace antibiotics, applied in animal feed, animal feed, bacteria used in food preparation, etc., can solve problems such as production performance impact, superinfection, antibiotic residues, etc.

Pending Publication Date: 2021-07-06
WUHAN SUNHY BIOLOGICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, with the extensive use of antibiotics in feed, it will cause the problem of drug resistance of pathogenic bacteria, causing many strange diseases in breeding, resulting in the inability of existing veterinary drugs to treat, and even spread to humans; and antibiotics will be used in livestock and poultry products such as meat, Residues in eggs and milk directly threaten human health and safety
In addition, the abuse of antibiotics will also destroy the micro-ecological balance in the intestinal tract, cause endogenous infection or superinfection of animals, and lead to the decline of cellular immunity and humoral immunity of livestock and poultry, thereby affecting production performance

Method used

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  • Feed additive capable of replacing antibiotics and preparation method thereof

Examples

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Effect test

Embodiment 1

[0024] This embodiment provides a feed additive to replace antibiotics, including the following components in parts by mass: 30 parts of compound oligosaccharides, 30 parts of compound probiotic bacteria slime, 15 parts of fermented garlic rod material, 5 parts of maltodextrin 10 parts, 10 parts of hydroxypropyl methylcellulose and probiotic protective agent; wherein, the probiotic protective agent is a mixture of skimmed milk powder, maltitol, sodium alginate, and gum arabic, and its mass ratio is 5:0.5:1:5 , the added amount of the probiotic protective agent is 10% of the mass of the compound probiotic slime.

[0025] Wherein, the preparation process of complex oligosaccharides is as follows: first, in the mixed raw material of corn bran, bran and palm meal, add its quality 10% by mannanase, cellulase, endo-xylanase Compound enzyme, enzymolysis at 50-70°C for 12 hours, enzymolysis water 50-80%, the mass ratio of corn bran, bran and palm meal in the mixed raw material is 3:2:...

Embodiment 2

[0030] This embodiment provides a feed additive to replace antibiotics, including the following components by mass fraction: 50 parts of compound oligosaccharides, 15 parts of compound probiotic bacteria slime, 10 parts of fermented garlic rod material, and 10 parts of maltodextrin , 15 parts of hydroxypropyl methylcellulose and a probiotic protective agent; wherein, the probiotic protective agent is a mixture of skimmed milk powder, maltitol, sodium alginate, and gum arabic, and its mass ratio is 5:0.5:1:5, The added amount of the probiotic protective agent is 10% of the mass of the compound probiotic slime.

[0031] Wherein, the preparation process of the composite oligosaccharide is roughly the same as the preparation process in the above-mentioned Example 1, the difference is that the mannanase activity in this example is 25000U / g, the cellulase activity is 3000U / g, The endo-xylanase activity is 170000U / g.

[0032] The preparation process of the compound probiotic bacteri...

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Abstract

The invention provides a feed additive capable of replacing antibiotics. The feed additive is prepared from the following components in parts by mass: 30-50 parts of compound oligosaccharide, 15-30 parts of compound probiotic bacterial sludge, 10-15 parts of a fermented garlic stem material, 5-20 parts of maltodextrin, 10-15 parts of hydroxypropyl methyl cellulose, and a probiotic protective agent; and the addition amount of the probiotic protective agent is 5-15% of the mass of the compound probiotic bacterial sludge. The compound probiotic bacterial sludge is obtained by culturing lactobacillus acidophilus and saccharomycetes; and the fermented garlic stem material is obtained by performing anaerobic fermentation on garlic stems through lactic acid bacteria, saccharomycetes, bacillus and compound enzyme. According the invention, the compound probiotic bacterial sludge is used as an active antibacterial component; the compound oligosaccharide is used as prebiotics; and the fermented garlic stem material is used as an auxiliary antibacterial component. Moreover, the probiotic protective agent is added for preparing the feed additive, so that the oligosaccharide fully acts with the probiotics to promote proliferation of the probiotics; and thus, the feed additive can enhance body immunity. In addition, the feed additive is also capable of achieving the effects of increasing nutrition and functionality of synbiotics while improving the immunity of the human body, thereby fulfilling the goal of partially replacing antibiotics and promoting growth.

Description

technical field [0001] The invention belongs to the technical field of feed additives, and in particular relates to a feed additive replacing antibiotics and a preparation method thereof. Background technique [0002] Since the 1940s, antibiotics have been widely used as feed additives in livestock and poultry farming. Under certain conditions, antibiotics can reduce the diarrhea rate of animals, regulate intestinal microbial flora, inhibit pathogenic bacteria and hosts from competing for nutrients, thereby improving Animal growth performance and feed utilization. [0003] However, with the extensive use of antibiotics in feed, it will cause the problem of drug resistance of pathogenic bacteria, causing many strange diseases in breeding, resulting in the inability of existing veterinary drugs to treat, and even spread to humans; and antibiotics will be used in livestock and poultry products such as meat, Residues in eggs and milk directly threaten human health and safety. ...

Claims

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Application Information

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IPC IPC(8): A23K50/75A23K10/20A23K20/163A23K10/18A23K10/12A23K10/37A23K10/14
CPCA23K50/75A23K10/20A23K20/163A23K10/18A23K10/12A23K10/37A23K10/14A23V2400/113Y02P60/87
Inventor 毛玲陶敏周明李亚峥詹志春周樱辜玲芳
Owner WUHAN SUNHY BIOLOGICAL
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