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Composition for resisting allergy and preventing and treating eczema as well as preparation method and application of composition

An anti-allergic and composition technology, applied in the field of cosmetic composition and preparation thereof, achieves the effects of reasonable formula design and safe and reliable raw materials

Pending Publication Date: 2021-05-25
上海创隆生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ointments currently on the market for treating skin problems generally contain ingredients such as hormones, antibiotics, and antihistamines, which have side effects and dependence

Method used

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  • Composition for resisting allergy and preventing and treating eczema as well as preparation method and application of composition
  • Composition for resisting allergy and preventing and treating eczema as well as preparation method and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1 Preparation of Composition 1

[0029] 1. Weigh 10 kg of Sophora flavescens, 10 kg of Qinpi, 1 kg of Angelica, 1 kg of Dihuang, 1 kg of Coptidis, 1 kg of Pulsatilla, and 1 kg of Fangfeng, and use a hammer mill (model WFJ-15, manufactured by Kanghe Machinery, Jiangyin City) Co., Ltd.) crushed through a 5-mesh sieve and set aside.

[0030]2. Put the pulverized material into a multifunctional dynamic extraction tank (model TT-500, Jining Jinbaite Biomechanical Co., Ltd.), and extract twice at 100±5°C. For the first time, water with 15 times the amount of raw materials was used for 60 minutes; for the second time, water with 10 times the amount of raw materials was used for 30 minutes, filtered through a 120-mesh sieve, and the filtrates were combined. 60L / hr) for microfiltration to collect the retentate. The retentate is concentrated by reverse osmosis membrane (molecular weight cut-off 100, permeate flow rate 90L / hr). The Brix value of the concentrated solution ...

Embodiment 2

[0031] Example 2 Preparation of Composition 2

[0032] 1. Weigh 5 kg of Sophora flavescens, 5 kg of Qinpi, 3 kg of Angelica, 3 kg of Dihuang, 1 kg of Coptidis, 1 kg of Pulsatilla, and 1 kg of Fangfeng, crush them with a hammer mill and pass through a 5-mesh sieve, and set aside.

[0033] 2. Put the pulverized material into the multifunctional dynamic extraction tank, and extract three times at 90±5°C. For the first time, water with 12 times the amount of raw materials is used for 45 minutes; for the second time, water with 10 times the amount of raw materials is used for 30 minutes; for the third time, water with 8 times the amount of raw materials is used for 15 minutes, and the filtrate is filtered through a 120-mesh sieve. Membrane (membrane pore size 0.2µm, permeate flow rate 60L / hr) is used for microfiltration, and the retentate is collected. The retentate is concentrated by reverse osmosis membrane (molecular weight cut-off 100, permeate flow rate 90L / hr), and the Brix v...

Embodiment 3

[0034] Example 3 Preparation of Composition 3

[0035] 1. Weigh 3kg of Sophora flavescens, 3kg of Qinpi, 6kg of Angelica, 6kg of Rehmannia glutinosa, 2kg of Coptis chinensis, 2kg of Pulsatilla chinensis, and 2 kg of Fangfeng, crush them through a 5-mesh sieve with a hammer mill, and set aside.

[0036] 2. Put the pulverized material into the multifunctional dynamic extraction tank, and extract three times at 80±5°C. For the first time, water with 10 times the amount of raw materials was used for 90 minutes; for the second time, water with 8 times the amount of raw materials was used for 60 minutes; for the third time, water with 5 times the amount of raw materials was used for 30 minutes, filtered through an 80-mesh sieve, and the filtrates were combined. Concentrate under reduced pressure (-0.06Mpa~-0.08Mpa, 70±5°C), the Brix value of the concentrated solution is 15.5%, the concentrated solution is pasteurized, poured into a sterile bag, and set aside. Dilute the concentrate...

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Abstract

The invention discloses a composition for resisting allergy and preventing and treating eczema. The composition is prepared from the following raw materials in parts by weight: 3 to 10 parts of radix sophorae flavescentis, 3 to 10 parts of cortex fraxini, 1 to 6 parts of radix angelicae sinensis, 1 to 6 parts of radix rehmanniae, 1 to 2 parts of rhizoma coptidis, 1 to 2 parts of radix pulsatillae and 1 to 2 parts of radix saposhnikoviae. The invention also discloses a preparation method of the composition, which comprises the following steps: (1) weighing the raw materials according to the formula proportion, conventionally crushing, adding water of which the weight is 5-15 times that of the raw materials, and extracting for 15-90 minutes for 2-3 times at the temperature of 80-100 DEG C; (2) mixing the extracting solutions in the step (1), and filtering to obtain supernate; and (3) concentrating the supernate in the step (2) to obtain a concentrated solution. The invention further discloses application of the composition to preparation of cosmetics for resisting allergy, preventing and treating eczema and mildly caring skin.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a composition in cosmetics and a preparation method and application thereof. Background technique [0002] As the first physiological defense line and the largest organ of the human body, the skin is always involved in the functional activities of the body. When people's skin is exposed to the air, the skin barrier is easily damaged, which in turn causes skin allergies, dermatitis, eczema, etc. Ointments currently on the market for treating skin problems generally contain ingredients such as hormones, antibiotics, and antihistamines, which have side effects and dependence. Recent studies have shown that for skin problems such as eczema, on the basis of drug treatment, skin care products with mild, moisturizing and moisturizing formulas can be used to effectively enhance skin resistance and play an auxiliary role in caring for the skin. [0003] Traditional Chinese ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K8/9789A61Q19/00A61P17/00A61P37/08
CPCA61K36/232A61K36/238A61K36/489A61K36/63A61K36/71A61K36/718A61K36/804A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61Q19/00A61K8/9789A61P17/00A61P37/08A61K2300/00
Inventor 王茵查王皓天张王姝妍王富华查满武
Owner 上海创隆生物技术有限公司
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