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A traditional Chinese medicine composition for treating type 2 diabetes insulin resistance

A technology for insulin resistance and type 2 diabetes, applied in drug combinations, pharmaceutical formulations, metabolic diseases, etc., can solve problems such as high cost, low success rate, and difficulty in explaining

Active Publication Date: 2022-05-27
山东康美德康新中医药产业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] With the rapid development of modern medical technology, the linear model of "single gene-single target-single disease" followed by traditional research and development has encountered huge bottlenecks and severe challenges. The cost is increasing and the success rate is getting lower and lower. Not only in Research on complex diseases and their medicines has encountered bottlenecks, and it is also difficult to explain the scientific connotation of traditional Chinese medicine that is clinically effective

Method used

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  • A traditional Chinese medicine composition for treating type 2 diabetes insulin resistance
  • A traditional Chinese medicine composition for treating type 2 diabetes insulin resistance
  • A traditional Chinese medicine composition for treating type 2 diabetes insulin resistance

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Preparation of Insulin Resistance Dropping Pills for Prevention and Treatment of Type 2 Diabetes:

[0057] Take 80 g of kaempferol, 120 g of hesperidin, 160 g of naringin, 90 g of apigenin, and 500 g of polyethylene glycol, heat to melt, mix well, transfer to the liquid reservoir of the pill-dropping machine, keep the temperature at 90 °C, drop in for cooling 1000g drop pills are made in the simethicone, and that is. Example 2

Embodiment 2

[0058] Preparation of Insulin Resistance Injection for Prevention and Treatment of Type 2 Diabetes:

[0059] Take 100 g of kaempferol, 90 g of hesperidin, 150 g of naringin, and 60 g of apigenin, add 1800 ml of water for injection, stir to dissolve, adjust the pH to 7.0-7.5 with saturated sodium hydroxide solution, add 10 g of activated carbon for injection, and add Water for injection to 2000ml, mix well, boil for 30 minutes, refrigerate, filter, add water for injection to 5000ml, filter with 0.45μm and 0.22μm microporous membranes respectively, pack each 5ml, fill with nitrogen, seal, circulate Steam sterilization for 30 minutes to obtain 1000 concentrated solutions for injection.

Embodiment 3

[0061] Preparation of capsules for prevention and treatment of type 2 diabetes insulin resistance:

[0062] Take 130 g of kaempferol, 180 g of hesperidin, 90 g of naringin, and 110 g of apigenin, add an appropriate amount of starch, mix well, put into capsules, and make 1,000 capsules.

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Abstract

The invention belongs to the field of research and development of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating insulin resistance of type 2 diabetes. The pharmaceutical composition is composed of 2-8 parts of kaempferol; 3-12 parts of hesperidin; 4-16 parts of naringin; and 3.5-14 parts of apigenin. The potency of the pharmaceutical composition prepared by the invention for treating type 2 diabetes insulin resistance can reach 98.58%. The pharmaceutical composition of the present invention does not contain the toxic components of pinellia calcium oxalate needle crystals and lectin protein, avoiding the inflammatory and stimulating effects of the original Wendan decoction on the human body, can be used with confidence, and the curative effect is enhanced; finally for further development Lay the foundation for the formulation of new active ingredient compositions.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine research and development, and particularly relates to a pharmaceutical composition for treating type 2 diabetes insulin resistance. Background technique [0002] The prevention and treatment of type 2 diabetes has been a research hotspot in recent years. Type 2 diabetes accounts for more than 90% of diabetic patients. Unlike type 1 diabetes, where the body has lost its ability to produce insulin, people with type 2 diabetes still produce insulin, but cannot use it effectively (medically known as "insulin resistance"). Insulin resistance is a common risk factor for type 2 diabetes and various cardiovascular diseases. Therefore, in the process of diabetes treatment, in addition to adequate protection of cell function, we should also pay attention to the improvement of insulin resistance. Only by starting from both aspects at the same time can we effectively inhibit the occurrence and de...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K31/352A61P3/10A61P5/50
CPCA61K31/7048A61K31/352A61P3/10A61P5/50A61K2300/00
Inventor 徐男王淑玲
Owner 山东康美德康新中医药产业发展有限公司
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