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A method for simultaneously extracting notoginseng saponins, notoginseng flavonoids and notoginseng polysaccharides and its application

A technology of Panax notoginseng flavonoids and Panax notoginseng polysaccharides, which is applied in the field of Panax notoginseng flavonoids and Panax notoginseng polysaccharides, and simultaneously extracts Panax notoginseng saponins, and can solve the problems such as insufficient utilization of Panax notoginseng medicinal materials.

Active Publication Date: 2022-04-01
SOUTHWEST FORESTRY UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention intends to provide a method for simultaneously extracting notoginseng saponins, notoginseng flavonoids and notoginseng polysaccharides, so as to solve the technical problem that notoginseng medicinal materials are not fully utilized

Method used

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  • A method for simultaneously extracting notoginseng saponins, notoginseng flavonoids and notoginseng polysaccharides and its application
  • A method for simultaneously extracting notoginseng saponins, notoginseng flavonoids and notoginseng polysaccharides and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Take 1 kg of Panax notoginseng medicinal material (the dried root of Panax notoginseng, the moisture content is controlled below 10%) and grind it through 40 meshes to obtain medicinal powder. Add an ethanol solution with a volume fraction of 80% to the medicinal powder (the percentages of all alcohol solutions in this scheme refer to volume percentages), to obtain the first extraction system, and extract by hot dipping at 70° C. for 3 hours. The dosage ratio of the 80% ethanol solution and the notoginseng medicinal material is 6L:1kg. Then filter to obtain extract I and dregs I. The extract I was evaporated and concentrated under reduced pressure, and then freeze-dried to obtain a dry powder extract of Panax notoginseng total saponins. The medicinal residue I is taken, and the culture solution and Bacillus cereus are added to the medicinal residue I to obtain a fermentation system. The addition of nutrient solution is the nutrient solution of every 1kg Panax notogins...

Embodiment 2

[0036] Take 2 kg of Panax notoginseng medicinal material (dried root, water content controlled below 10%), pulverize and pass through 40 meshes to obtain medicinal powder. Add an ethanol solution with a volume fraction of 70% to the medicinal powder to obtain the first extraction system, and extract by hot dipping at 60° C. for 3 hours. The dosage ratio of the 70% ethanol solution and the notoginseng medicinal material is 5L:1kg. Then filter to obtain extract I and dregs I. The extract I was evaporated and concentrated under reduced pressure, and then freeze-dried to obtain a dry powder extract of Panax notoginseng total saponins. Take the dregs I, and add culture solution and Bacillus cereus (Bacillus cereus) to the dregs I 14579), to obtain a fermentation system. The addition of nutrient solution is the nutrient solution of every 1kg Panax notoginseng medical material corresponding 3L, and the inoculum amount (quality) of bacillus cereus is 8% of the quality of fermentati...

Embodiment 3

[0038] Take 5 kg of Panax notoginseng medicinal material (dried root, water content controlled below 10%), pulverize and pass through 40 meshes to obtain medicinal powder. Add an ethanol solution with a volume fraction of 90% to the medicinal powder to obtain a first extraction system, and extract by hot soaking at 80° C. for 2 hours. The dosage ratio of the 90% ethanol solution and the notoginseng medicinal material is 8L:1kg. Then filter to obtain extract I and dregs I. The extract I was evaporated and concentrated under reduced pressure, and then freeze-dried to obtain a dry powder extract of Panax notoginseng total saponins. Take the dregs I, and add culture solution and Bacillus cereus (Bacillus cereus) to the dregs I 14579), to obtain a fermentation system. The addition of nutrient solution is the nutrient solution of every 1kg Panax notoginseng medical material corresponding 3L, and the inoculum amount (quality) of Bacillus cereus is 12% of the quality of fermentati...

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Abstract

The invention relates to the technical field of plant natural product preparation, in particular to a method for simultaneously extracting notoginseng saponins, notoginseng flavonoids and notoginseng polysaccharides and its application. The extraction method comprises the following steps carried out in sequence: using an ethanol solution with a volume fraction of 70-90% to perform hot-dip extraction on the medicinal powder; then using Bacillus cereus to ferment the medicinal residue to obtain a final fermentation system; The functional components in the system are extracted to obtain the extract II and the dregs II; finally, the dregs II are extracted with microwave assistance to obtain the extract III. Among them, the extract I, extract II and extract III contain Panax notoginseng saponins, Panax notoginseng flavonoids and Panax notoginseng polysaccharides respectively, and the above active ingredients have good antioxidant activity. The preparation method of this scheme can be applied to the practical operation of the preparation of antioxidants, and provide raw materials with excellent properties for the preparation and research and development of related medicines and cosmetics.

Description

technical field [0001] The invention relates to the technical field of plant natural product preparation, in particular to a method for simultaneously extracting notoginseng saponins, notoginseng flavonoids and notoginseng polysaccharides and its application. Background technique [0002] The medicinal material Panax notoginseng is the dried root of Panax notoginseng (Burk.) F.H.Chen, an Araliaceae plant. It has good hemostatic effect, promotes the division and growth of various blood cells, and can significantly increase the number of red blood cells in the pathological model of hemorrhagic anemia. Anemia has a good therapeutic effect. The total saponins of Panax notoginseng are the most important functional components in Panax notoginseng, and have been extensively studied and clinically applied. However, among the medicinal materials of Panax notoginseng, the functional components worthy of further use are far more than the total saponins of Panax notoginseng. Panax noto...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/258A61K31/715A61P39/06A61K8/9789A61K8/73A61Q19/08C08B37/00A61K125/00
Inventor 施蕊何霞红王澍邓国宾熊冰杰
Owner SOUTHWEST FORESTRY UNIVERSITY
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