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Toothpaste for oral ulcer

A technology for oral ulcers and toothpaste, applied in the field of toothpaste research, can solve the problem that oral ulcers cannot be effectively cured, and achieve the effects of inhibiting dental plaque, reducing gingivitis and promoting healing

Pending Publication Date: 2021-04-13
福建爱洁丽日化有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the deficiencies of the prior art, the present invention provides a toothpaste for oral ulcers, which solves the problem that the existing oral ulcers cannot be cured with special effects, and the present invention has the functions of inhibiting dental plaque, reducing gingivitis, and promoting the healing of recurrent oral ulcers. Effect

Method used

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  • Toothpaste for oral ulcer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A kind of toothpaste for oral ulcer, described friction agent 34%, sorbitol 46%, surfactant 2.0%, menthol 0.2%, sodium azulene sulfonate 0.2%, dipotassium glycyrrhizinate 0.3%, thickener 1 %, 0.2% sucralose, 1.2% food grade flavor, 0.6% honeysuckle flower extract, 14.3% purified water;

Embodiment 2

[0017] A toothpaste for oral ulcers, the ingredients in the toothpaste are: 34% abrasive, 46% sorbitol, 2.4% surfactant, 0.2% menthol, 0.6% sodium azulene sulfonate, glycyrrhizic acid Dipotassium 0.6%, thickener 1%, sucralose 0.2%, food grade flavor 1.4%, honeysuckle flower extract 0.7%, purified water 12.9%;

Embodiment 3

[0019] A toothpaste for oral ulcers, the ingredients in the toothpaste are: 34% friction agent, 46% sorbitol, 2.8% surfactant, 0.3% menthol, 0.9% sodium azulene sulfonate, glycyrrhizic acid in the toothpaste Dipotassium 0.9%, thickener 1.2%, sucralose 0.3%, food-grade essence 1.6%, honeysuckle flower extract 0.8%, purified water 11.2%.

[0020] For the toothpaste of different proportions, the toothpaste of the above-mentioned embodiment is assessed in use, each embodiment is assessed in batches, and the number of individuals assessed in each embodiment is 20 patients with oral ulcers, and the use time is three days;

[0021]

[0022] Efficiency calculation result = no obvious effect + obvious effect + can be completely cured;

[0023] Among them, 0 points are invalid, 1 point is not obvious effect, 4 points are obvious effect, and 5 points are completely cured;

[0024] Efficiency = {not obvious effect (1 point) X number of people + obvious effect (4 points) X number of pe...

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Abstract

The invention discloses toothpaste for oral ulcer. The toothpaste comprises the following components in percentage by weight: 20-40% of an abrasive, 30-60% of sorbitol, 2.0-3.0% of a surfactant, 0.1-0.3% of menthol, 0.01-1.0% of sodium gualenate, 0.2-1.0% of dipotassium glycyrrhizinate, 0.8-1.3% of a thickening agent, 0.1-0.4% of sucralose, 0.8-2.0% of food-grade essence, 0.5-1.0% of a honeysuckle flower extract and the balance of purified water. The toothpaste for oral ulcer takes sodium gualenate as a key functional component; sodium gualenate is safe and non-toxic; the killing rate of sodium gualenate on streptococcus mutans, staphylococcus aureus, candida albicans and escherichia coli reaches 99.98% or above; the killing rate of sodium gualenate on porphyromonas gingivalis reaches 98.14% or above; and the toothpaste has the remarkable effects of inhibiting dental plaque, relieving gingivitis and promoting healing of recurrent oral ulcer.

Description

technical field [0001] The invention relates to the technical field of toothpaste research, in particular to a toothpaste for oral ulcers. Background technique [0002] Recurrent oral ulcers, also known as recurrent aphth, recurrent aphthous stomatitis, and recurrent aphthous ulcers, are the most common type of oral mucosal diseases, such as common cold, indigestion, nervousness, depression, etc. All can cause the occurrence of the disease by chance, and it is more likely to occur on the lips, cheeks, tongue edge, etc., and can appear in any part of the mucous membrane. . Recurrent oral ulcers are self-limiting and can heal in about 10 days. Its incidence rate in the normal population is 10% to 30%. At present, there is no effective radical cure method, and the clinical treatment is still mainly to promote local wound healing. [0003] Clinically, recurrent oral ulcers are treated mainly by anti-inflammatory, pain-relieving, antiseptic, and wound healing promotion methods...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/63A61K8/46A61K31/255A61Q11/00A61P1/02A61P31/02A61P31/04A61P31/10
CPCA61K8/466A61K8/63A61K8/9789A61Q11/00A61P1/02A61K31/255A61P31/04A61P31/10A61P31/02A61K2800/28Y02A50/30
Inventor 陈万金蔡丽萍黄强
Owner 福建爱洁丽日化有限公司
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