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Application of deer tail in preparation of products for treating gout and hyperuricemia

A technology for hyperuricemia and gout, applied in the field of medicine, can solve the problems of less deer tails, lack of systemicity, and pharmacological effects that need to be discovered, and achieve the effect of improving hyperuricemia

Pending Publication Date: 2021-03-12
INST OF SPECIAL ANIMAL & PLANT SCI OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few and systematic studies on deer tail, and its pharmacological effects need to be explored

Method used

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  • Application of deer tail in preparation of products for treating gout and hyperuricemia
  • Application of deer tail in preparation of products for treating gout and hyperuricemia
  • Application of deer tail in preparation of products for treating gout and hyperuricemia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A processing method of deer tail: the specific steps are as follows:

[0031] (1) Take the sika deer tail, wash and chop the sika deer tail, then place it in an electric constant temperature blast drying oven to dry at 40°C, and then crush the sika deer tail;

[0032] (2) Mix and soak the pulverized sika deer tail obtained in step (1) and water according to a mass ratio of 1:10, and then heat and reflux the mixed solution at 100°C for 1 hour to obtain a water extract;

[0033] (3) The water extract obtained in step (2) is centrifuged at 4500r / min for 10min, then the supernatant is taken, the residue is repeatedly heated and refluxed for 2 times, combined 3 times to obtain the supernatant extract, concentrated and dried to obtain Water extract of deer tail, the extraction rate is 15.79%.

[0034] Use the following experiments to verify the experimental results:

[0035] 1. Experimental method:

[0036] 1. Animal feeding: 48 SPF grade male Kunming mice (20±2g), 24 SPF ...

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Abstract

The invention discloses application of deer tail in preparation of products for treating gout and hyperuricemia, and belongs to the field of medicines. The invention aims to effectively treat and relieve gout symptoms. According to the application of deer tail in preparation of a product for treating gout and hyperuricemia, the application is implemented as follows: cleaning sika deer tails, chopping the tails, performing drying in an electric heating constant-temperature blast drying oven, performing pulverizing, adding the product into water, carrying out heating reflux extraction at 100 DEGC to obtain a water extract, centrifuging the supernatant, taking the supernate, and repeatedly extracting the residues twice, combining the three-time supernatant, performing concentrating and drying to obtain the deer tail water extract. Pharmacological experiment results show that the deer tail water extract has the effect of resisting gouty arthritis by reducing the swelling rate of ankle joints of rats and reducing the levels of IL-1, IL-6 and TNF-alpha inflammatory factors in serum, and the deer tail water extract has the effect of inhibiting uric acid, creatinine and urea nitrogen in serum of mice suffering from hyperuricemia and has the effect of improving hyperuricemia.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of deer tail in the preparation of products for treating gout and hyperuricemia. Background technique [0002] With the improvement of people's living standards, more and more high-protein and high-purine foods are consumed, which overloads the uric acid in the body, and the occurrence of hyperuricemia is due to the disorder of the purine metabolism system in the body, which leads to uric acid in the body. A metabolic disease with increased synthesis or decreased excretion. Its clinical manifestation is that blood urate is higher than 420 μmol / L in men and higher than 360 μmol / L in women. Hyperuricemia and acute gouty arthritis are different stages of gout occurrence and development. When the uric acid content exceeds the maximum solubility in the human body, it will be deposited in the joints and surrounding tissues in the form of urate crystals, thereby indu...

Claims

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Application Information

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IPC IPC(8): A61K35/12A61P19/06A61P19/02A23L33/10
CPCA61K35/12A61P19/06A61P19/02A23L33/10A23V2002/00A23V2200/30A23V2250/204
Inventor 孙印石李志满
Owner INST OF SPECIAL ANIMAL & PLANT SCI OF CAAS
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