Spiral pipe structure for separation column of high-speed counter-current chromatograph

Abstract

The spiral pipe structure comprises the separation column, a spiral square pipe and two adjusting blocks, each adjusting block is of a circular ring structure, the separation column is sleeved with the hollow portion of each adjusting block, the end faces of the sides, close to each other, of the two adjusting blocks are inclined planes, and the two inclined planes are parallel to each other. Thespiral square pipe is spirally wound on the separation column and arranged between the two adjusting blocks, the two sides of the spiral square pipe abut against the two adjusting blocks respectively,a pipe inlet hole and a pipe outlet hole are formed in the first disc, and the two ends of the spiral square pipe extend out of the pipe inlet hole and the pipe outlet hole respectively; the end, extending out of the pipe inlet hole, of the spiral square pipe penetrates through the adjusting block close to one side of the first disc, the cross section of the spiral square pipe is of a rectangularstructure, the long edge of the rectangular structure is parallel to the axis of the separation column. By means of the device, the technical problems existing in the prior art can be solved: when atwo-phase interface in the circular tube is eccentric, radial mixing is insufficient, and the axial inclination of the spiral tube is difficult to control.

Description

technical field [0001] The invention relates to the field of separation columns of high-speed countercurrent chromatographs, in particular to a spiral tube structure used for separation columns of high-speed countercurrent chromatographs. Background technique [0002] High-speed Countercurrent Chromatography (HSCCC for short), a new, continuous and efficient liquid-liquid partition chromatography technology developed by Dr. Ito of the National Institutes of Health in 1982, is different from other chromatography technologies. No solid carrier is needed, so it can avoid adverse effects such as contamination, inactivation, denaturation and irreversible adsorption of the sample caused by the reaction between the surface of the solid carrier and the sample. At the same time, it also has the advantages of wide application range, fast speed, large injection volume, low cost and high recovery rate. Therefore, it has been widely used in the fields of biology, medicine, food, materia...

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Problems solved by technology

[0004] In view of the above-mentioned shortcoming of the prior art, the object of the present invention is to: provide a kind of helical tube structure that is used for the separation column of high-speed countercurrent chromatograph, solve the technical problem existing in the prior art, such as: the two phases in the circular tube When the interface is eccentric, the radial mixing is insufficient and the axial inclination of the spiral tube is not easy to control

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