Method for establishing rat periodontitis model

Abstract

The invention provides a method for establishing a rat periodontitis model, and belongs to the technical field of periodontology. The rat periodontitis model is established by injecting drugs into a plurality of rats to be modeled; the rats suffering from periodontitis are divided into a hard food feeding group and a soft food feeding group, hard food is fed to the rats suffering from periodontitis in the hard food feeding group, and soft food is fed to the rats suffering from periodontitis in the soft food feeding group; and maxilla specimens in molar regions at the two sides of the rats suffering from periodontitis are separated, and local tissues are scanned to confirm the establishment of a mechanical load composite model of the rats suffering from periodontitis . Through iconographicanalysis on to-be-modeled tissues of the rats, it is proved that the pathological change of the local periodontal tissues of the rats suffering from periodontitis is detected by changing the hardnessof the food, and the pathological process of clinical dentition defects accompanied by periodontitis affected teeth is fully simulated; and an innovative method is provided for designing and researching dentures of patients with periodontal diseases and dentition defects accompanied by the periodontal diseases.

Description

technical field [0001] The invention relates to the technical field of periodontology, in particular to a method for establishing a rat periodontitis model. Background technique [0002] "Missing teeth" in today's society - missing or missing dentition has become the primary oral problem that plagues middle-aged and elderly people in my country, which will have adverse effects on patients' masticatory function, appearance, and temporomandibular function. According to the viewpoint of contemporary stomatology, it is necessary to maintain the patient’s remaining teeth as much as possible to prevent the elderly from entering the stage of dentition loss prematurely, and middle-aged and elderly patients with dentition loss are often accompanied by chronic periodontitis of varying degrees. There are great risks in designing dentures with the remaining teeth of the patient as abutments, which greatly increases the difficulty of restoring missing teeth. How to make full use of the ...

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Problems solved by technology

Through literature search, it is found that some scholars are currently trying to study the establishment of animal models of periodontitis with occlusal trauma, but no relevant research has been found on establishing a composite model of periodontitis rat mechanical loads by changing the hardness of food, so the present invention has certain innovations sex

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