A low-temperature storage and transportation device without active cooling based on multi-layer phase change materials

Abstract

The invention discloses a low-temperature storage and transportation device without active cooling based on a multi-layer phase change material, which belongs to the field of low-temperature preservation of biological materials. The device comprises multiple alternately arranged phase change material layers and thermal insulation layers, the biological material to be preserved is arranged in the center of the innermost phase change material layer, and the phase change temperature zone of the phase change material layer adjacent to the biological material is equal to or lower than The target storage temperature, along the direction from the inside to the outside, the phase change temperature regions of each phase change material layer are sequentially increased or equal. The invention can adapt to the requirements of storage and transportation temperature and effective storage time required by different biological materials, can achieve longer effective storage time under the same space conditions, and can use relatively less liquid nitrogen for low-temperature storage and transportation in the liquid nitrogen temperature zone. The amount of nitrogen achieves a longer effective storage time.

Description

technical field [0001] The invention belongs to the field of cryogenic preservation of biological materials, in particular to a low-temperature storage and transportation device without active cooling based on multilayer phase change materials. Background technique [0002] At room temperature, biological materials such as isolated cells, tissues, and organs cannot survive for a long time without maintaining their physiological properties. The metabolism in organisms is subject to the Arrhenius (Arrhenius) relation: k=Aexp(-E / RT), where k is the biochemical reaction rate, A is the Arrhenius factor, E is the activation energy, and R is the gas constant , T is the thermodynamic temperature. It can be seen that low temperature can inhibit the biochemical activities of organisms. In view of this, cryopreservation is often used in medicine, pharmaceuticals, food, agriculture and other fields. At present, the temperature zones commonly used for the preservation of biological ma...

AI Technical Summary

Problems solved by technology

Even so, the problem of gas generated by the vaporization of liquid nitrogen is still unavoidable, which limits the use of this type of cryogenic storage and transportation device in some occasions. For example, in air transportation, liquid nitrogen is clearly listed as a dangerous product, and its use must be reduced as much as possible quantity

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