Traditional Chinese medicine composition for preventing ulcerative colitis

Abstract

The invention discloses a traditional Chinese medicine composition which is mainly prepared from the following traditional Chinese medicine monomers including puerarin, berberine, baicalein, glycyrrhizic acid and magnolol. Experimental results show that rat colitis treated by the traditional Chinese medicine composition is obviously relieved, the weight loss, bloody stool, diarrhea and disease activity index (DAI) score is reduced, the colon length is shortened, and the colon mucosal lesion index (CMDI) score and histological score are reduced, so that the traditional Chinese medicine composition disclosed by the invention has good effects of resisting ulcerative colitis and damp-heat syndrome diarrhea, and has a wide application prospect in the research aspect of related medicines. Besides, the problems of unclear components and unclear mechanisms of a traditional Chinese medicine compound in the past are solved through a traditional Chinese medicine monomer formula, the limitation toresearch and application is broken through, and a new thought and help are provided for subsequent research, development, optimization and innovation of traditional Chinese medicines.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine composition for preventing ulcerative colitis. Background technique [0002] Inflammatory bowel disease (Inflammatory Bowel Disease, IBD) is an autoimmune chronic inflammatory disease of the intestinal tract that requires lifelong management, mainly including Crohn's disease (Crohn Disease, CD) and ulcerative colitis (Ulcerative Colitis, UC) . UC is more common than CD, and its main clinical symptoms are bloody diarrhea, abdominal pain, mucopurulent stool, weight loss, etc. The whole course of the disease is long and repeated. Ulcerative colitis has developed into a global disease, and is even called "green cancer" because of its recurrent and long-term characteristics. [0003] Due to the special geographical environment in the Lingnan area, resulting in the local high temperature and high humidity climate characteristics, ...

AI Technical Summary

Problems solved by technology

From the perspective of the formation and development of Chinese medicine, the curative effect of traditional Chinese medicine prescriptions is far superior to any single drug component. However, due to the complex components of crude drugs and crude drug compounds, in-depth research on

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