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Novel tooth whitening gel and preparation method and application thereof

A technology of tooth whitening and whitening gel, which is applied in the field of tooth whitening to achieve the effect of improving tooth brightness, reducing irritation, and good whitening effect

Pending Publication Date: 2021-01-01
SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Aiming at the adverse reactions and problems of the prior art, combined with the advantages of the persulfate activation system, the present invention provides an efficient and safe non-hydrogen peroxide tooth whitening gel, which achieves a good tooth whitening effect and is more biologically safe. High, less irritation to pulp tissue

Method used

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  • Novel tooth whitening gel and preparation method and application thereof
  • Novel tooth whitening gel and preparation method and application thereof
  • Novel tooth whitening gel and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Dissolve 2 g of disodium hydrogen phosphate and 0.22 g of potassium dihydrogen phosphate in 100 mL of deionized water, fully dissolve with a magnetic stirrer at a speed of 300-350 r / min, stir for 5-10 min, and adjust the pH value to 7.2-7.5 to obtain Activator, after fully reacting 5mL activator with 0.8g potassium hydrogen persulfate, add 0.4g silicon dioxide and mix, stir evenly and let stand to get Gel A.

Embodiment 2

[0034] Dissolve 0.3g of sodium pyrophosphate in 5mL of deionized water, fully dissolve with a magnetic stirrer at a speed of 300-350r / min, stir for 5-10min to form an activator, and then fully react with 1.2g of potassium hydrogen persulfate, then add 0.4g of silicon dioxide was mixed, stirred evenly and left to stand to obtain gel B.

Embodiment 3

[0036] Dissolve 1g of sodium tripolyphosphate in 5mL of deionized water, fully dissolve with a magnetic stirrer at a speed of 300-350r / min, stir for 5-10min to form an activator, and then fully react with 1.2g of potassium hydrogen persulfate, then add 0.8g of sodium alginate was mixed, stirred evenly and left to stand to obtain gel C.

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Abstract

The invention discloses novel tooth whitening gel and a preparation method thereof. The novel tooth whitening gel comprises an oxidizing agent, an activating agent, a thickening agent and water. The preparation method of the novel tooth whitening gel comprises the following steps that after the corresponding activating agent is fully reacted with the oxidizing agent according to a certain mass ratio, the thickening agent is added and mixing is carried out, uniform stirring is carried out, and standing is carried out to obtain the novel tooth whitening gel. Phosphate is used for activating persulfate to obtain the whitening gel containing oxygen free radicals, so that the degradation of pigments in tooth hard tissues is realized, the whitening effect is achieved, and meanwhile, the demineralization of the enamel surface and the adverse stimulation to dental pulp cells can be effectively reduced.

Description

technical field [0001] The invention relates to a novel non-hydrogen peroxide whitening gel containing persulfate, belonging to the technical field of tooth whitening. Background technique [0002] In today's society, people have a strong desire to seek teeth whitening, and some psychological studies have also shown that people with whiter teeth are more likely to obtain positive, positive self-evaluation and good social attractiveness. The main components of existing tooth whitening gels are hydrogen peroxide (HP) or carbamide peroxide (CP), which are decomposed by catalysts or lasers to generate perhydroxy anions and oxygen free radicals, which can effectively destroy the tooth tissue. The double bond in the dyeing group decomposes the pigment in the superficial layer of enamel and dentin, turning it into a substance with a smaller molecular weight, and the absorption peak changes from visible light to ultraviolet light, and finally achieves tooth whitening. However, if t...

Claims

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Application Information

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IPC IPC(8): A61K8/23A61K8/04A61Q11/00
CPCA61K8/23A61K8/042A61Q11/00
Inventor 孙皎杨甦汪俊刘昕隋佰延
Owner SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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