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Application of nano-silver in preparing cosmetics or medicines for preventing and removing bromhidrosis, liquid and preparation method of liquid

A technology of nano silver and cosmetics, applied in the field of liquid preparation and preparation thereof, can solve the problems of frequent wiping, limited effect and high recurrence rate, and achieve the effect of remarkable effect, remarkable effect and good environmental protection.

Pending Publication Date: 2020-12-29
成都志俊时代科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Drugs or cosmetics containing fragrance substances can temporarily remove body odor, but the disadvantage is that the effect is limited, it needs to be wiped frequently, and the recurrence rate is high. At present, there is still a lack of a long-term deodorant for removing body odor
[0004] Nano-silver is a simple substance of metallic silver with a particle size of nano-scale. It has a strong antibacterial and bactericidal effect. It is generally used in antibacterial and anti-inflammatory cosmetics. At present, there are no reports on the application of nano-silver in the prevention and removal of body odor.

Method used

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  • Application of nano-silver in preparing cosmetics or medicines for preventing and removing bromhidrosis, liquid and preparation method of liquid

Examples

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Effect test

preparation example Construction

[0033] The present invention also provides the preparation method of the liquid preparation for preventing and removing body odor described in the above scheme, comprising the following steps:

[0034] The nano-silver sol and polydopamine (PDA) solution are mixed and reacted so that the polydopamine is coated on the surface of the nano-silver to obtain a liquid agent for preventing and removing body odor; the reaction time is 0.5-2 hours.

[0035] In the present invention, the preparation method of the nano-silver sol includes two methods, respectively method one or method two, which are introduced respectively below:

[0036] Method 1: Polyvinylpyrrolidone (PVP), silver nitrate and alcohol are mixed and reacted to obtain nano-silver sol.

[0037] In the present invention, the mixing process is preferably: dissolving polyvinylpyrrolidone in alcohol to obtain a polyvinylpyrrolidone solution, dissolving silver nitrate in alcohol to obtain a silver nitrate solution, and then diss...

Embodiment 1

[0053] (1) Weigh polyvinylpyrrolidone (PVP) powder and dissolve it in absolute alcohol to prepare an alcohol solution with a mass fraction of 2.0%. Weigh silver nitrate (AgNO 3 ) solid is dissolved in 95% alcohol solution to form an alcohol solution with a mass fraction of 2.0%. At room temperature, the PVP alcohol solution was added to the AgNO 3 In the alcohol solution, the volume ratio is controlled at 1:1. After stirring for 10 minutes, it turns light yellow. Continue stirring for about 3 hours to obtain a red rice-colored nano-silver sol. The concentration of nano-silver is 2700mg / L, and the average particle size is 4-6nm. Left and right, recorded as liquid A.

[0054] (2) Dopamine was weighed to prepare a 1000 mg / L aqueous solution, and 1 mol / L sodium hydroxide solution was added dropwise with stirring at room temperature to adjust the pH value to 7.5-8.5. After stirring for about 15 minutes, the solution turned bright yellow and then dark brown. Continue to stir the...

Embodiment 2

[0057] Steps (1)~(2) are identical with embodiment 1, and step (3) is as follows:

[0058] Preparation of a liquid preparation with a nanosilver concentration of 30mg / L: at normal temperature, get liquid A and dilute to 95% of the volume of the target liquid, then add 1000mg / L of liquid C under ultrasonic stirring (the amount of liquid C is the target liquid. 5% of the volume) nano-silver is coated, adjust the PDA content in the mixed solution to be 50mg / L, react 2h, obtain the reddish brown nano-silver solution that the silver content is 30mg / L PDA coating. Add a small amount of 1.0mol / L sodium hydroxide or nitric acid solution dropwise to adjust the pH to 6.5-7.5. Sealed in a dark bottle, away from light, and stored at room temperature.

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Abstract

The invention relates to the technical field of deodorization cosmetics and provides application of nano-silver in preparing cosmetics or medicines for preventing and removing bromhidrosis, liquid anda preparation method of the liquid. The nano-silver is used to prepare cosmetics or medicines for preventing and removing bromhidrosis, the new use of the nano-silver is provided, besides, the nano-silver is high in safety, good in environmental protection property, outstanding in sterilization performance and remarkable in preventing and removing the bromhidrosis. The provided liquid comprises nano-silver, polydopamine coating a surface of the nano-silver, and a solvent. The polydopamine is coated on the surface of the nano-silver, stability of the product can be remarkably improved, and theproduct can be stored under conventional conditions, the polydopamine has strong adhesion force, can be firmly adhered to surfaces of hair and skin, prevents the nano-silver from losing due to sweatand friction effects, and achieves effects of long-term sterilization and deodorization. Furthermore, concentration of the nano-silver in the provided liquid is relatively low, so that cost of the liquid can be further reduced.

Description

technical field [0001] The invention relates to the technical field of deodorant cosmetics, in particular to the application of nano silver in the preparation of cosmetics or medicines for preventing and removing body odor, a liquid preparation and a preparation method thereof. Background technique [0002] Body odor is also known as underarm odor, stinky sweat, etc. The odor is produced by the decomposition of various secretions of the apocrine sweat glands on the skin surface through the decomposition of resident bacteria (staphylococcus, gram-negative bacilli, etc.) on the skin. Unsaturated fatty acids with special unpleasant odor, the most important of which is trans-3-ethyl-2-hexenoic acid. Human body armpits, groin, feet, perianal, vulva, umbilical fossa, and women's breasts can all occur, with feet and armpits being the most common. Investigations show that the incidence rate of underarm odor in western countries can be as high as 95%, and that in eastern countries i...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K47/32A61K47/34A61K47/10A61K33/38A61P17/00A61K8/19A61K8/81A61K8/84A61Q15/00
CPCA61K9/0014A61K9/08A61K47/32A61K47/10A61K33/38A61P17/00A61K8/19A61K8/8176A61K8/84A61Q15/00
Inventor 但会英但建明汪宇但淼
Owner 成都志俊时代科技有限公司
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