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Side-excitation ultrasonic processor and processing method

An ultrasonic processing and processor technology, applied in the field of biological sample processing devices, can solve the problems of low energy utilization efficiency, uneven sound field energy distribution, low processing efficiency, etc. Evenly distributed effect

Active Publication Date: 2021-11-12
珠海艾博罗生物技术股份有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Contact ultrasonic processors have problems such as low processing efficiency, sample cross-contamination, and must be operated in an open manner, while non-contact ultrasonic processors generally use the bottom excitation method of ultrasonic transducers, which has uneven energy distribution in the sound field and low energy utilization efficiency. question

Method used

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  • Side-excitation ultrasonic processor and processing method
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  • Side-excitation ultrasonic processor and processing method

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Embodiment approach

[0051] According to a preferred embodiment of the present invention, the width of the sample processing tank 2 is set to:

[0052]

[0053] or

[0054] or d<λ / 4 (three)

[0055] In the formula, d represents the width of the sample processing tank 2,

[0056] λ represents the wavelength,

[0057] Wherein, the value of n is a non-negative integer, preferably 0-10, more preferably 0-5.

[0058] The width d of the sample processing tank 2 should be as small as possible while satisfying the structural size requirements. When the sample processing tank 2 adopts acoustic field resonance to process samples, the width d of the sample processing tank 2 adopts the setting method of formula (1 or 2);

[0059] When the near-acoustic field is used to process samples in the sample processing tank 2, the width d of the sample processing tank 2 adopts the setting method of formula (3);

[0060] In the case where the wavelength of the acoustic wave and the number and arrangement of the...

Embodiment 1

[0070] When the speed of sound in the solution is 1500m / s, and the width of the sample processing tank 2 is d=31.25mm (5λ / 4), at figure 1 The excitation voltage with a frequency of 60kHz is applied to a plurality of piezoelectric transducers 1 at the same time, and the piezoelectric transducers 1 work simultaneously in the sample processing tank 2 to generate a resonant sound field, and the cavitation effect is used to treat the samples placed on the sample test tube holder 3. The biological sample in the test tube is processed, and the water circulation hole 4 on the sample processing tank 2 is used to keep the temperature in the processing tank 3 constant.

Embodiment 2

[0072] When the speed of sound in the solution is 1500m / s, and the sample processing tank 2 width d=20mm, in figure 1 The excitation voltage with a frequency of 60 kHz is applied to a plurality of piezoelectric transducers 1 at the same time, and the piezoelectric transducers 1 work at the same time to generate a uniformly distributed near-acoustic field in the sample processing tank 2, and use the cavitation effect to treat the sample placed on the test tube holder 3 The biological sample in the sample test tube is processed, and the water circulation hole 4 on the sample processing tank 2 is used to keep the temperature in the processing tank 2 constant.

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Abstract

The invention discloses a side excitation type ultrasonic processor, which mainly includes a piezoelectric transducer, a sample processing tank and a sample test tube support. Multiple piezoelectric transducers are used to excite the sound field inside the sample processing tank from the side, and the sound field is evenly distributed. At the same time, both sides of the piezoelectric transducer are attached to the two sample tanks to improve energy utilization.

Description

technical field [0001] The invention relates to a biological sample processing device, in particular to a side-excitation ultrasonic processor and a processing method. Background technique [0002] Ultrasound has a cavitation effect in liquid, and the use of ultrasonic cavitation effect to process biological samples such as cells and tissues in the container can achieve a crushing effect. At present, there are two main methods of ultrasonic biological sample crushing: contact type and non-contact type. The contact type ultrasonic processor uses the ultrasonic probe to directly contact the sample solution for processing; the non-contact ultrasonic processor uses the ultrasonic transducer to emit sound waves to the sample solution. The sample is processed through the sample test tube inside the sample processing tank. Contact ultrasonic processors have problems such as low processing efficiency, cross-contamination of samples, and must be operated in an open manner, while non...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B02C19/18B06B1/06
CPCB02C19/18B06B1/06B06B2201/55
Inventor 胡俊辉苏松飞郑乐郑末晶柳林
Owner 珠海艾博罗生物技术股份有限公司
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