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Application of pharmaceutical composition to preparation of drugs for treating vertigo caused by vertebrobasilar insufficiency

A technology of basilar artery and composition, which is applied in the direction of drug combination, plant/algae/fungus/moss components, blood diseases, etc., to achieve the effect of good safety, significant curative effect and high content of active ingredients

Inactive Publication Date: 2020-09-25
GUIZHOU MAQIKA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The above-mentioned medicinal materials are authentic medicinal materials in the southwest region, and are also commonly used by the local ethnic minorities in Guizhou and Chongqing, especially the Miao people. At present, it has not been seen that the five medicinal materials, including Coptidis Rhizome, Heqi, Rehmannia, Turmeric, and Scutellaria, have been used together to treat cerebrovascular diseases. reports of related diseases

Method used

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  • Application of pharmaceutical composition to preparation of drugs for treating vertigo caused by vertebrobasilar insufficiency
  • Application of pharmaceutical composition to preparation of drugs for treating vertigo caused by vertebrobasilar insufficiency
  • Application of pharmaceutical composition to preparation of drugs for treating vertigo caused by vertebrobasilar insufficiency

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Experimental program
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Effect test

Embodiment 1

[0154] The extraction of embodiment 1 pharmaceutical composition

[0155] Recipe: 290g Coptidis, 870g Hongqi, 870g Rehmannia, 800-864g Turmeric, 580g Scutellaria

[0156]Preparation method: take Coptis chinensis and turmeric and heat and reflux with 60% ethanol to extract three times, soak for 1 hour for the first time, extract for 1 hour, extract for 50 minutes for the second and third times, combine the extracts, filter, and recover the filtrate with ethanol and concentrate to a relative density of 1.00- 1.05 (60°C), set aside; decoct medicinal dregs, red qi and rehmannia root twice with water, soak for 1 hour for the first time, boil for 1.3 hours for the second time, and boil for 1 hour for the second time, combine the decoction, filter, and let the filtrate stand for 24 hours , filtered, the filtrate was combined with Coptis Rhizoma and Turmeric extract, concentrated to a clear paste with a relative density of 1.15-1.20 (60°C), filtered, and 15.38 g of steviol was added t...

Embodiment 2

[0158] The extraction of embodiment 2 pharmaceutical compositions

[0159] Recipe: 265g Coptidis, 795g Hongqi, 795g Rehmannia, 795g Turmeric, 530g Scutellaria

[0160] Preparation method: extract the composition according to the method described in Example 1.

Embodiment 3

[0161] The extraction of embodiment 3 pharmaceutical compositions

[0162] Recipe: Weigh 288g of Coptidis Rhizome, 864g of Heqi, 864g of Rehmannia, 864g of Turmeric, 576g of Scutellaria, set aside;

[0163] Preparation method: extract the composition according to the method described in Example 1.

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Abstract

The invention relates to application of a pharmaceutical composition to preparation of drugs for treating vertigo caused by vertebrobasilar insufficiency. Raw materials of the pharmaceutical composition are genuine traditional Miao herbs including rhizoma coptidis (Miao dialect: Wang Lianjing), radix hedysari (Miao dialect: Dou Xiao), rhizoma rehmanniae (Miao dialect: Fei Ta), rhizoma curcumae Longae (Miao dialect: Wo Ha) and radix scutellariae (Miao dialect: E Ga). The pharmaceutical composition is applied to the vertigo caused by stroke, stroke sequela, ischemia, hemorrhage, posthemorrhagicedema, reperfusion injury, thrombosis, vasoconstriction, infarction and presenile dementia and various reasons. In addition, animal experiments verify the therapeutic effect of the pharmaceutical composition of the invention in treating cerebrovascular or related diseases, and the pharmaceutical composition has the function of regulating body functions, thus providing another choice for patients.

Description

[0001] The present invention is a divisional application with the application number 2017101045075, the filing date is February 24, 2017, and the title of the invention is "Application of a Pharmaceutical Composition in the Preparation of Drugs for Treating Cerebrovascular or Related Diseases". technical field [0002] The invention relates to the application of a pharmaceutical composition in the preparation of medicine for treating vertigo caused by vertebra-basilar artery insufficiency. Background technique [0003] Coptidis, Miao language is Wabgeleencnaemx (transliterated as Wang Lian stem), is a perennial herb, has the effect of clearing heat and dampness, purging fire and detoxifying; nature and flavor are bitter, cold; Guixin, spleen, stomach, liver, gallbladder, large intestine meridian; mainly used For damp and hot fullness, vomiting and acid regurgitation, diarrhea, jaundice, high fever and coma, hyperactivity of heart fire, upset and insomnia, vomiting of blood he...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P9/10A61P25/00A61P1/08A61P7/02A61P25/28
CPCA61K36/48A61K36/539A61K36/718A61K36/804A61K36/9066A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61P1/08A61P7/02A61P9/10A61P25/00A61P25/28A61K2300/00
Inventor 张芝庭张涛涛
Owner GUIZHOU MAQIKA PHARMA
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