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Acne-removing gel and preparation method thereof

A gel and anti-acne technology, which is applied in the field of anti-acne gel and its preparation, can solve the problems of reducing the utilization rate of efficacy substances, affecting skin absorption, hindering wound healing, etc., and achieves improved anti-acne effect, simple process, and easy to use value effect

Active Publication Date: 2020-08-25
上海九乙生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, a large part of acne-prone skin is sensitive skin, plus acne can cause damage to the stratum corneum, and it is easy to cause pain, hinder wound healing and other adverse reactions after contact with alcohol
In addition, alcohol-containing acne products, as the alcohol volatilizes, the originally dissolved salicylic acid precipitates and becomes a solid crystal state again, which affects skin absorption and reduces the utilization rate of efficacy substances

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Add 10g of Poloxamer 407 to 100g of deionized water at room temperature, and place it in a refrigerator at 5°C for 8 hours; add 1g of salicylic acid to 10g of propylene glycol; heat to 45°C to dissolve; take out the completely dissolved poloxamer 407 aqueous solution, pour the dissolved salicylic acid propylene glycol solution slowly, and stir until uniform at room temperature.

Embodiment 2

[0021] Add 10g of Poloxamer 407 to 50g of deionized water at room temperature, and place it in a refrigerator at 5°C for 10 hours; add 1g of salicylic acid to 7.5g of propylene glycol; heat to 50°C to dissolve; take out the completely dissolved poloxamer M407 aqueous solution, slowly pour the dissolved propylene glycol salicylic acid solution, and stir until uniform at room temperature.

Embodiment 3

[0023] Add 10g of Poloxamer 407 to 50-100g of deionized water at room temperature, and place it in a refrigerator at 5°C for 12 hours; add 1g of salicylic acid to 5g of propylene glycol; heat to 55°C to dissolve; take out the completely dissolved poloxamer Sham 407 aqueous solution, slowly pour the dissolved salicylic acid propylene glycol solution, and stir until uniform at room temperature.

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PUM

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Abstract

The invention provides acne-removing gel and a preparation method thereof, and belongs to the field of cosmetics. The acne-removing gel is prepared by dissolving salicylic acid in propylene glycol andthen adding poloxamer 407, wherein the mass ratio of the propylene glycol to the poloxamer 407 is 1: (1-2). The invention also discloses a preparation method of the acne-removing gel. The salicylic acid is dissolved through the propylene glycol, so that the irritation of the acne-removing gel to the skin and acnes is reduced, and meanwhile, the utilization rate of functional substances is increased.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to an acne-removing gel and a preparation method thereof. Background technique [0002] Salicylic acid is a fat-soluble organic acid, which can dissolve the forming substances between cuticles and make the cuticles fall off, so it can remove the thick cuticles and promote metabolism. Salicylic acid acts on the cells of the hair follicle wall, which can help remove blocked hair follicles, correct abnormal cell shedding, and help acne caused by blocked pores. Therefore, salicylic acid is often used in acne products. Salicylic acid is only slightly soluble in water, but easily soluble in ethanol, ether, chloroform, etc., so many products often add alcohol as a solvent for salicylic acid. However, a large part of acne-prone skin is sensitive skin, and acne can cause damage to the stratum corneum. After contact with alcohol, it is very easy to cause pain, hinder wound healing and other adverse...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/368A61K8/34A61K8/86A61K8/04A61Q19/00A61P17/10
CPCA61K8/368A61K8/345A61K8/86A61K8/042A61Q19/00A61P17/10Y02A50/30
Inventor 张小燕邱瑞林
Owner 上海九乙生物科技有限公司
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