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Multi-modal parameter model optimization fusion method based on image omics features

A radiomics and parametric model technology, applied in the field of medical image processing and analysis, can solve problems such as the lack of radiomics calculation process and model parameter tuning, to reduce errors, improve modeling accuracy, and improve interpretability Effect

Pending Publication Date: 2020-07-28
JILIN UNIV FIRST HOSPITAL
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  • Application Information

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Problems solved by technology

Researchers have developed open source software platforms IBEX and QIFE in the direction of radiomics, but the content of the platform only includes image processing and simple modeling, and does not have a complete radiomics calculation process and model parameter tuning functions

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  • Multi-modal parameter model optimization fusion method based on image omics features
  • Multi-modal parameter model optimization fusion method based on image omics features
  • Multi-modal parameter model optimization fusion method based on image omics features

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Embodiment Construction

[0076] The present invention will be further described in detail below in conjunction with the accompanying drawings, so that those skilled in the art can implement it with reference to the description.

[0077] Such as figure 1 As shown, the multimodal parameter model optimization fusion method based on radiomics features provided by the present invention includes:

[0078] Step S110, acquiring medical images of various modalities, and performing preprocessing on the medical images;

[0079] Step S120, perform region segmentation on the preprocessed medical image, and obtain the region of interest corresponding to each modality medical image;

[0080] After image preprocessing, the automatically extracted ROI image or manually drawn ROI image can be used;

[0081] Among them, the method of automatically extracting ROI includes ROI after segmentation based on deep learning. Most of the automatically extracted ROIs belong to a single ROI of a certain disease. On the premise o...

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Abstract

The invention discloses a multi-modal parameter model optimization fusion method based on image omics features. The method comprises the following steps: obtaining medical images of a plurality of modes, and preprocessing the medical images; performing region segmentation on the preprocessed medical images to obtain a region of interest corresponding to each modal medical image; obtaining a high-dimensional imaging omics feature corresponding to each region of interest; dividing the high-dimensional image omics features to obtain a training set and a test set, and performing gradient dimensionality reduction to obtain low-dimensional image omics feature tags; and training a plurality of candidate parameter models by using the low-dimensional imaging omics feature tags as a cross training data set and using different algorithms. A subject working feature curve is drawn, the area mean value under the subject working feature curve is calculated, and the area mean value with the highest area mean value is determined as the optimal parameter model, so that the image features can be effectively extracted, and medical image information can be mined to the maximum extent.

Description

technical field [0001] The invention relates to the field of medical image processing and analysis, in particular to a multimodal parameter model optimization and fusion method based on radiomics features. Background technique [0002] Radiomics is an emerging research field in recent years that aims to extract and analyze medical images to establish models that may improve the accuracy of diagnosis, prognosis, and prediction. With the development of radiomics, more researchers have gradually joined the field and discussed and improved some of them. At present, in the field of omics, radiomics has been combined with genomics to establish predictive models. [0003] Most radiomics research uses Matlab software or Python platform to extract radiomics features. Since Matlab is a semi-open source software, it is not convenient to view and modify the underlying functions, so it cannot be conveniently used by every researcher. [0004] With the popularity of artificial intellige...

Claims

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Application Information

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IPC IPC(8): G06T7/00G06T7/11G06T7/45G06T7/62G06K9/32G06K9/62G06N20/20
CPCG06T7/0012G06T7/11G06T7/45G06T7/62G06N20/20G06T2207/10081G06T2207/30004G06T2207/20104G06V10/25G06F18/253G06F18/214
Inventor 张惠茅李雪妍李明洋苗政郭钰
Owner JILIN UNIV FIRST HOSPITAL
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